The reaction medium plays a key role in the definition of sustainable yet efficient synthetic methodologies. In order to replace classic toxic organic solvents, promising effective and safer alternatives can be found among the chemicals derived from the valorization of waste. In this article we summarize our recent finding on the use of Rhodiasolv Polarclean as a safe solvent derived from Nylon 66 manufacturing waste. The use of Polarclean has led to the definition of waste-minimized copper catalyzed azide-alkyne cycloaddition (CuAAC) and palladium-catalyzed C–H functionalization reaction. By exploiting its peculiar physical properties, this solvent may offer in some conditions, a valid alternative to toxic polar aprotic solvents for the definition of effective synthetic tools.
Polarclean from waste valorization of Nylon 66 manufacturing: A sustainable solvent for organic synthesis
Vaccaro L.
;Santoro S.;Luciani L.;Ferlin F.
2019
Abstract
The reaction medium plays a key role in the definition of sustainable yet efficient synthetic methodologies. In order to replace classic toxic organic solvents, promising effective and safer alternatives can be found among the chemicals derived from the valorization of waste. In this article we summarize our recent finding on the use of Rhodiasolv Polarclean as a safe solvent derived from Nylon 66 manufacturing waste. The use of Polarclean has led to the definition of waste-minimized copper catalyzed azide-alkyne cycloaddition (CuAAC) and palladium-catalyzed C–H functionalization reaction. By exploiting its peculiar physical properties, this solvent may offer in some conditions, a valid alternative to toxic polar aprotic solvents for the definition of effective synthetic tools.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
