Orange juice associated with a balanced diet mitigated risk factors of metabolic syndrome: A randomized controlled trial

Nenhuma Miniatura disponível

Data

2019-09-01

Autores

Ponce, Olivia [UNESP]
Benassi, Renata [UNESP]
Cesar, Thais [UNESP]

Título da Revista

ISSN da Revista

Título de Volume

Editor

Resumo

In this 12 weeks randomized parallel controlled trial, we investigated whether the daily intake of orange juice (OJ) associated with a balanced diet attenuates risk factors in individuals with metabolic syndrome (MetS) and reverses this condition. Patients were divided into two groups: control (n = 36) and OJ (n = 36), which adopted a balanced diet according to the MetS guidelines. In addition, the OJ group consumed 500 mL/d OJ, maintaining the recommended dietary energy intake but adding more vitamin C (133%) and folic acid (43%) than controls. After the intervention, both groups showed a mean reduction of glucose (−3%), cholesterol (−7.5%), HDLC (−8%), BMI (−2%), waist circumference (−5.5%), and systolic and diastolic blood pressure (−8% and −9.5%, respectively). However, only the OJ group decreased insulin (−9%), insulin resistance (- 8%), LDL-C (−4%), CRP (−28%) and higher hsCRP levels (−61%), while the control group reduced exclusively triglycerides (−8.4%). Both groups showed a slight increase in antioxidant capacity (1%). The reversion of MetS to normality was similar in both groups: 12 out of 36 controls (33%) and 13 out of 36 subjects supplemented with OJ (36%). MetS reversal was due to a decrease in the risk factors, such as systolic pressure in the controls, and high glucose, insulin resistance, systemic inflammation and LDL-C, without altering HDL-C, in the OJ group. In conclusion, both treatments reduced risk factors and together reversed more than 30% MetS to normal, but the addition of OJ mitigated more risk factors than the balanced diet alone. (NCT 03301675).

Descrição

Palavras-chave

Balanced diet, Glycemia, Inflammation, Insulin resistance, Metabolic syndrome, Orange juice

Como citar

Journal of Nutrition and Intermediary Metabolism, v. 17.

Coleções