Platelets are essential for primary hemostasis and repair of the endothelium, but they also play a key role in the development of acute coronary syndromes and contribute to cerebrovascular events. In addition, they participate in the process of forming and extending atherosclerotic plaques. Atherosclerosis is a chronic inflammatory process, and inflammation is an important component of acute coronary syndromes. The relation between chronic and acute vascular inflammation is unclear, but platelets are a source of inflammatory mediators, and the activation of platelets by inflammatory triggers may be a critical component of atherothrombosis. This review article describes the role of platelets...

Platelet Activation in Atherothrombosis.

DAVI', Giovanni;
2007-01-01

Abstract

Platelets are essential for primary hemostasis and repair of the endothelium, but they also play a key role in the development of acute coronary syndromes and contribute to cerebrovascular events. In addition, they participate in the process of forming and extending atherosclerotic plaques. Atherosclerosis is a chronic inflammatory process, and inflammation is an important component of acute coronary syndromes. The relation between chronic and acute vascular inflammation is unclear, but platelets are a source of inflammatory mediators, and the activation of platelets by inflammatory triggers may be a critical component of atherothrombosis. This review article describes the role of platelets...
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/133634
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