A pregnant woman with acute hepatitis B virus (HBV) infection had her second pregnancy terminated at 25 weeks' gestation because of fetal ascites and ventriculitis. Meconium peritonitis was also found at autopsy. No HBV DNA but cytomegalovirus (CMV) DNA was detected in the fetal liver and ascitic fluid. Recurrent maternal CMV infection was demonstrated by pre-existing CMV IgG antibodies, high IgG avidity and low IgM levels. After abortion, the patient developed chronic active hepatitis. Nevertheless, having become pregnant again with a new partner, she had an uneventful third pregnancy and gave birth to a healthy boy.
Multi-system cytomegalovirus fetopathy by recurrent infection in a pregnant woman with hepatitis B / Giovanni, Nigro; LA TORRE, Renato; Manuela, Mazzocco; Federica, Coacci; Barbara, Riosa; Claudia, D'Emilio; Cosmi, Ermelando. - In: PRENATAL DIAGNOSIS. - ISSN 0197-3851. - 19:11(1999), pp. 1070-1072. [10.1002/(sici)1097-0223(199911)19:11<1070::aid-pd701>3.0.co;2-a]
Multi-system cytomegalovirus fetopathy by recurrent infection in a pregnant woman with hepatitis B
LA TORRE, Renato;COSMI, Ermelando
1999
Abstract
A pregnant woman with acute hepatitis B virus (HBV) infection had her second pregnancy terminated at 25 weeks' gestation because of fetal ascites and ventriculitis. Meconium peritonitis was also found at autopsy. No HBV DNA but cytomegalovirus (CMV) DNA was detected in the fetal liver and ascitic fluid. Recurrent maternal CMV infection was demonstrated by pre-existing CMV IgG antibodies, high IgG avidity and low IgM levels. After abortion, the patient developed chronic active hepatitis. Nevertheless, having become pregnant again with a new partner, she had an uneventful third pregnancy and gave birth to a healthy boy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
