The stabilizing action of C(α)-tetrasubstituted α-amino acids inserted into a sequence of short peptides allowed for the first time the preparation of water-soluble nanoparticles of different materials coated with a helix-structured undecapeptide. This peptide coating strongly favors nanoparticle uptake by human immune system cells.

Water-soluble peptide-coated nanoparticles: Control of the helix structure and enhanced differential binding to immune cells

TAVANO, REGINA;CAUSIN, VALERIO;PAPINI, EMANUELE;MANCIN, FABRIZIO;MORETTO, ALESSANDRO
2011

Abstract

The stabilizing action of C(α)-tetrasubstituted α-amino acids inserted into a sequence of short peptides allowed for the first time the preparation of water-soluble nanoparticles of different materials coated with a helix-structured undecapeptide. This peptide coating strongly favors nanoparticle uptake by human immune system cells.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2434707
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