Down regulation of poly(ADP-ribose)polymerase (ADPRP) activity was observed in mouse LW-cells after treatment with 2'-5'oligoadenylates or with fibroblast interferon and poly(rI) poly(rC). The poly(rI) poly(rC)-induced inhibition of the enzymatic activity correlates with the observed increase of endogenous 2',5'-oligoadenylate cores which were reported to be potent inhibitors of ADPRP in vitro.

TORNESE BUONAMASSA, D., Malanga, M., Coccia, E.M., Romeo, G., Affabris, E., Farina, B.A.S.H. (1989). Poly (ADP-ribose) polymerase activity is inhibited by 2'-5'-oligoadenylates in mouse L-cells. FEBS LETTERS, 258(1), 163-165 [10.1016/0014-5793(89)81641-2].

Poly (ADP-ribose) polymerase activity is inhibited by 2'-5'-oligoadenylates in mouse L-cells

AFFABRIS, Elisabetta;
1989-01-01

Abstract

Down regulation of poly(ADP-ribose)polymerase (ADPRP) activity was observed in mouse LW-cells after treatment with 2'-5'oligoadenylates or with fibroblast interferon and poly(rI) poly(rC). The poly(rI) poly(rC)-induced inhibition of the enzymatic activity correlates with the observed increase of endogenous 2',5'-oligoadenylate cores which were reported to be potent inhibitors of ADPRP in vitro.
1989
TORNESE BUONAMASSA, D., Malanga, M., Coccia, E.M., Romeo, G., Affabris, E., Farina, B.A.S.H. (1989). Poly (ADP-ribose) polymerase activity is inhibited by 2'-5'-oligoadenylates in mouse L-cells. FEBS LETTERS, 258(1), 163-165 [10.1016/0014-5793(89)81641-2].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11590/114903
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