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Journal Article

Catalysis-Based Total Synthesis of Latrunculin B

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Fürstner,  Alois
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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De Souza,  Dominic
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Parra-Rapado,  Liliana
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Jensen,  Jon Tangaa
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Citation

Fürstner, A., De Souza, D., Parra-Rapado, L., & Jensen, J. T. (2003). Catalysis-Based Total Synthesis of Latrunculin B. Angewandte Chemie, International Edition, 42(43), 5358-5360. doi:10.1002/anie.200352413.


Cite as: https://hdl.handle.net/11858/00-001M-0000-000F-98E3-5
Abstract
The highly selective actin-binding latrunculins (e.g. 1) play a prominent role as probe molecules in chemical biology. A highly concise, productive, and inherently flexible approach to 1 illustrates the excellent profile and use of metal-catalyzed C-C bond formations.