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One-pot, three-component synthesis of novel δ-sultam scaffolds via N-sulfonylation—intramolecular Michael sequences.

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Kia,  R.
Research Group of Structural Dynamics of (Bio)Chemical Systems, MPI for Biophysical Chemistry, Max Planck Society;

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Citation

Ghandi, M., Nazari, S. H., Bozcheloei, A. H., Sadeghzadeh, M., & Kia, R. (2011). One-pot, three-component synthesis of novel δ-sultam scaffolds via N-sulfonylation—intramolecular Michael sequences. Tetrahedron Letters, 52(49), 6613-6615. doi:10.1016/j.tetlet.2011.09.146.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002C-16F3-2
Abstract
The synthesis of novel δ-sultam scaffolds utilizing one-pot, three-component reactions of 1,3-dicarbonyl compounds, primary aliphatic amines and substituted styrenesulfonyl chlorides is reported. A variety of six-membered sultams are obtained in moderate to good yields presumably via N-sulfonylation—intramolecular Michael addition sequences.