Homo- and heteronuclear 2D NMR approaches to analyse a mixture of deuterated 
unlike/like stereoisomers using weakly ordering chiral liquid crystals

Ben Ali, Karim; Lafon, Olivier; Zimmermann, Herbert; Guittet, Eric; Lesot, Philippe

doi:10.1016/j.jmr.2007.04.007

Datensatz

DATENSATZ AKTIONENEXPORT

Zur Ablage hinzufügen

Lokale TagsFreigabegeschichteDetailsÜbersicht

Freigegeben

Zeitschriftenartikel

Homo- and heteronuclear 2D NMR approaches to analyse a mixture of deuterated unlike/like stereoisomers using weakly ordering chiral liquid crystals

MPG-Autoren

/persons/resource/persons128263

Zimmermann, Herbert
Department of Molecular Physics, Max Planck Institute for Medical Research, Max Planck Society;
Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society;

Externe Ressourcen

http://www.sciencedirect.com/science/article/pii/S109078070700122X/pdfft?md5=abd9ac6f439c57d9d78d59be5d072da2&pid=1-s2.0-S109078070700122X-main.pdf
(beliebiger Volltext)

http://dx.doi.org/10.1016/j.jmr.2007.04.007
(beliebiger Volltext)

Volltexte (beschränkter Zugriff)

Für Ihren IP-Bereich sind aktuell keine Volltexte freigegeben.

Volltexte (frei zugänglich)

Es sind keine frei zugänglichen Volltexte in PuRe verfügbar

Ergänzendes Material (frei zugänglich)

Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar

Zitation

Ben Ali, K., Lafon, O., Zimmermann, H., Guittet, E., & Lesot, P. (2007). Homo- and heteronuclear 2D NMR approaches to analyse a mixture of deuterated unlike/like stereoisomers using weakly ordering chiral liquid crystals. Journal of Magnetic Resonance, 187(2), 205-215. doi:10.1016/j.jmr.2007.04.007.

Zitierlink: https://hdl.handle.net/11858/00-001M-0000-002C-ABAC-5

Zusammenfassung

We describe several homo- and heteronuclear 2D NMR strategies dedicated to the analysis of anisotropic 2H spectra of a mixture of dideuterated unlike/like stereoisomers with two remote stereogenic centers, using weakly orienting chiral liquid crystals. To this end, we propose various 2D correlation experiments, denoted “D(H)nD” or “D(H)nC” (with n = 1, 2), that involve two heteronuclear polarization transfers of INEPT-type with one or two proton relays. The analytical expressions of correlation signals for four pulse sequences reported here were calculated using the product-operators formalism for spin I = 1 and S = 1/2. The features and advantages of each scheme are presented and discussed. The efficiency of these 2D sequences is illustrated using various deuterated model molecules, dissolved in organic solutions of polypeptides made of poly-γ-benzyl-l-glutamate (PBLG) or poly-ε-carbobenzyloxy-l-lysine (PCBLL) and NMR numerical simulations.