2011-11-09
Structural and Functional Studies on the Ubiquitin-Specific Protease Family
Publication
Publication
Structurele en functionele studies op de ubiquitine-specifieke protease familie
When RNA translation has completed and the proteins have been properly folded, most proteins are subject to a diverse range of post-translational modifications that affect their function. It is an important cellular strategy that enables the cell to react dynamically to intracellular or environmental changes caused by exposure to stress factors, growth stimuli or differentiation signals. Proteins are modified by methylation, acetylation, hydroxylation, phosphorylation or conjugated to ubiquitin (Ub) and ubiquitin-like (Ubl) proteins. The posttranslational modification with Ub of proteins has emerged to play an essential role in the regulation of virtually all aspects of cell biology.
| Additional Metadata | |
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| This research was financially supported by Rubicon Network of Excellence (EU), KWF (Koningin Wilhelmina Fonds) and NWO-CW (Nederlandse organisatie voor de wetenschappelijk onderzoek - chemische wetenschappen, CBG (Centre for Biomedical Genetics) and Antoni van Leeuwenhoek Hospital | |
| T.K. Sixma (Titia) | |
| Erasmus University Rotterdam | |
| hdl.handle.net/1765/26844 | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Vargas, M. (2011, November 9). Structural and Functional Studies on the Ubiquitin-Specific Protease Family. Retrieved from http://hdl.handle.net/1765/26844 |
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| Additional Files | |
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| 3398_Vargas, Mark Patrick Alexander.jpg Cover Image , 41kb | |
| stellingen Luna Vargas.pdf , 35kb | |
