Abstract

This thesis contains of: 1) Studies describing the pathogenesis of infantile haemangioma 2) The development of a novel scoring system for infantile haemangioma activity 3) Studies evaluating different therapy options for infantile haemangioma

Hypoxia is important in the pathogenesis of infantile haemangioma but the exact mechanism is not clear yet. As for the therapy, when treatment is necessary, propranolol has become the first choice of treatment but for topical use the best option and concentration is not yet clear. Therefore more research is still necessary!

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A.P. Oranje (Arnold) , M.A.M. van Steensel
The studies reported in this thesis were conducted at the Departments of Paediatric Surgery, Paediatrics, Paediatrics – unit Paediatric Dermatology, and Pathology, Erasmus MC and Erasmus MC – Sophia Children’s Hospital, University Medical Center Rotterdam, Rotterdam, the Netherlands, and at the Department of Dermatology, Maastricht University Medical Center, Maastricht, the Netherlands. Financial support for research and publication of this thesis was provided by a grant from KWF Kankerbestrijding (Dutch Cancer Society): UM 2009-4605; GROW, School for Oncology and Developmental Biology; A*STAR, Agency for Science, Technology, and Research, Singapore; Project Aardbeesie, Stichting InFace; Stichting ter Bevordering van de Kinderdermatologie Rotterdam (Foundation for Paediatric Dermatology Rotterdam); Abbott B.V.; AbbVie/Shire; BAP Medical; patiëntenvereniging CMTC-OVM; Fagron; Galderma Benelux B.V.; patiëntenvereniging HEVAS; Mölnlycke Health Care; Neocare B.V.; Pierre Fabre Benelux (Hemangiol®); L’Oréal (La Roche-Posay); Pharmaline B.V.; Department of Paediatric Surgery, Erasmus MC, University Medical Center Rotterdam; RCCR Rotary Club Bussum; Xerox (Nederland) B.V.; SNS Bank; Lancom B.V. Automatisering; eDesigndogs; Cysonet; SecuWatch Beveiliging; E2E Software; Het Vlakke Land; Dierengeluk; RM-Webcreation; Stichting Lijf en Leven; Bas van Toor (clown Bassie); Mirjam Aret; Sophia Trappers (dhr. Bax); Feyenoord voetbal clinic; Kids in Bizz (groep 8 van basisschool De Fontein, Krimpen aan den IJssel); Senioren Big Band Rotterdam; World Baseball Tournament, Rotary Capelle aan den IJssel; en Apotheek IJsselmonde (Roné van der Weele).
hdl.handle.net/1765/77221
Erasmus MC: University Medical Center Rotterdam

Janmohamed, S. (2014, December 4). Infantile Haemangioma: Pathogenesis, Evaluation, and Therapy. Retrieved from http://hdl.handle.net/1765/77221