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Stress and child inflammation: the role of caregiving

URL to cite or link to: http://hdl.handle.net/1802/33298

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PDF of thesis.
Thesis (Ph. D.)--University of Rochester. Department of Clinical and Social Psychology, 2017.
Research in adults indicates a pathway from socio-demographic early risk and adversity and later disease. One hypothesized pathway is through inflammatory processes. This relationship is not well-understood from a developmental perspective and this study sought to explore these pathways as well as the parent-child relationship as a potential mediator. Using data as part of a larger study, the current study used a longitudinal design collecting self-report, observational, and biological data at 4 visits over 2 years. A multilevel model approach was used to portray the changes in the data over time. The results characterize child IL-6 levels within visits as well as the change and stability over time. Second, this work indicated that the pathways from socio-demographic stress are largely confounded by body mass index. Finally, a small but consistent link was found between parent negative behavior and child IL-6. This is significant and merits further investigation; the finding that negative interactions with one’s caregiver may be associated with an inflammatory response is relevant for both general and mental health care providers.
Contributor(s):
Anne Shepherd Burke (1979 - ) - Author

Thomas G. O'Connor - Thesis Advisor

Primary Item Type:
Thesis
Identifiers:
LCSH Parent and child--Case studies.
LCSH Stress in children--Case studies.
LCSH Inflammation--Mediators--Case studies.
Local Call No. AS38.612
LCSH Interleukin-6.
Language:
English
Subject Keywords:
Stress; Parenting; Child; IL-6; Cytokines
Sponsor - Description:
National Institutes of Health (NIH) - HD038938
National Center for Research Resources (NCRR) - General Clinical Research Grant 5MO1 RR00044
First presented to the public:
8/31/2019
Originally created:
2017
Date will be made available to public:
2019-08-31   
Original Publication Date:
2017
Previously Published By:
University of Rochester
Place Of Publication:
Rochester, N.Y.
Citation:
Extents:
Illustrations - illustrations
Number of Pages - xii, 131 pages
License Grantor / Date Granted:
Maggie Dull / 2017-12-28 12:03:43.926 ( View License )
Date Deposited
2017-12-28 12:03:43.926
Date Last Updated
2018-01-04 09:09:43.075
Submitter:
Maggie Dull

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