Association between Stress and Antiretroviral Therapy Adherence among Women Living with HIV in Toronto, Ontario: Assessment of Correlates, Mediation and Moderation
Advisor:
Loutfy, Mona
Department:
Health Policy, Management and Evaluation
Issue Date:
Mar-2015
Abstract (summary):
This cross-sectional study sought to: "Determine the association between stress, depression and ART adherence among women living with and accessing care for HIV in Toronto, Ontario, between 2007 and 2012". Using OCS data, logistic regression models were used to identify covariates of (≥95%) adequate adherence and mediators and moderators in the association between stress and adherence. Among 307 women, 34.5% and 65.5% had poor and adequate adherence, respectively. Women with poor versus adequate adherence had more reports of hazardous alcohol use, stress events and depressive symptoms. No hazardous alcohol use (aOR=2.20, 95%CI:1.12-4.32) and fewer stress events (aOR=0.56, 95%CI:0.33-0.94) were associated with increased odds of adequate adherence. The association between environmental stress and adequate adherence was attenuated among women ≤35 years (aOR=0.73, 95%CI:0.56-0.94) versus ≥45 years (aOR=0.51, 95%CI:0.34-0.77). Interventions to improve adherence and ensure levels ≥95% must address stress and promote adaptive coping strategies to reduce or eliminate hazardous alcohol use.
Permanent Link:
https://hdl.handle.net/1807/72345
Content Type:
Thesis
Items in TSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
link to htmlmap