Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/46935
Título: | 3D segmentation of intervertebral discs: from concept to the fabrication of patient-specific scaffolds |
Autor(es): | Oner, T. Cengiz, I. F. Pitikakis, M. Cesario, L. Parascandolo, P. Vosilla, L. Viano, G. Oliveira, J. M. Reis, R. L. Silva-Correia, Joana |
Palavras-chave: | 3D bioprinting Intervertebral disc MRI segmentation Patient-specific approach Rapid prototyping Reverse Engineering Tissue engineering |
Data: | Mar-2017 |
Editora: | Future Medicine |
Revista: | Journal of 3D Printing in Medicine |
Citação: | Oner T., Cengiz I. F., Pitikakis M., Cesario L., Parascandolo P., Vosilla L., Viano G., Oliveira J. M., Reis R. L., Silva-Correia J. 3D segmentation of intervertebral discs: From concept to the fabrication of patient-specific scaffolds, Journal of 3D Printing in Medicine, Vol. 1, Issue 2, pp. 91-101, doi:10.2217/3dp-2016-0011, 2017 |
Resumo(s): | Aim: To develop a methodology for producing patient-specific scaffolds that mimic the annulus fibrosus (AF) of the human intervertebral disc (IVD) by means of combining magnetic resonance imaging (MRI) and 3D bioprinting. Methods: In order to obtain the AF 3D model from patientâ s volumetric MRI dataset, the RheumaSCORE segmentation software was used. Polycaprolactone scaffolds with three different internal architectures were fabricated by 3D bioprinting, and characterized by micro-computed tomography. Results: The demonstrated methodology of a geometry reconstruction pipeline enabled to successfully obtain an accurate AF model and 3D print patient-specific scaffolds with different internal architectures. Conclusion: The results guide us towards patient-specific IVD tissue engineering as demonstrated a way of manufacturing personalized scaffolds using patient's MRI data. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/46935 |
ISSN: | 2059-4755 |
e-ISSN: | 2059-4763 |
Versão da editora: | http://www.futuremedicine.com/doi/abs/10.2217/3dp-2016-0011 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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18985-3dp-2016-0011_Oner.pdf | 6,75 MB | Adobe PDF | Ver/Abrir |