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Postbiotics and their health modulatory biomolecules

Emma Scott (UGent) , Kim De Paepe (UGent) and Tom Van de Wiele (UGent)
(2022) BIOMOLECULES. 12(11).
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Abstract
Postbiotics are a new category of biotics that have the potential to confer health benefits but, unlike probiotics, do not require living cells to induce health effects and thus are not subject to the food safety requirements that apply to live microorganisms. Postbiotics are defined as a "preparation of inanimate microorganisms and/or their components that confers a health benefit on the host". Postbiotic components include short-chain fatty acids, exopolysaccharides, vitamins, teichoic acids, bacteriocins, enzymes and peptides in a non-purified inactivated cell preparation. While research into postbiotics is in its infancy, there is increasing evidence that postbiotics have the potential to modulate human health. Specifically, a number of postbiotics have been shown to improve gut health by strengthening the gut barrier, reducing inflammation and promoting antimicrobial activity against gut pathogens. Additionally, research is being conducted into the potential application of postbiotics to other areas of the body, including the skin, vagina and oral cavity. The purpose of this review is to set out the current research on postbiotics, demonstrate how postbiotics are currently used in commercial products and identify a number of knowledge gaps where further research is needed to identify the potential for future applications of postbiotics.
Keywords
postbiotics, gut health, epithelial barrier, microbiome, exopolysaccharides, bacteriocins, SCFAs, butyrate, antioxidant

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Citation

Please use this url to cite or link to this publication:

MLA
Scott, Emma, et al. “Postbiotics and Their Health Modulatory Biomolecules.” BIOMOLECULES, vol. 12, no. 11, 2022, doi:10.3390/biom12111640.
APA
Scott, E., De Paepe, K., & Van de Wiele, T. (2022). Postbiotics and their health modulatory biomolecules. BIOMOLECULES, 12(11). https://doi.org/10.3390/biom12111640
Chicago author-date
Scott, Emma, Kim De Paepe, and Tom Van de Wiele. 2022. “Postbiotics and Their Health Modulatory Biomolecules.” BIOMOLECULES 12 (11). https://doi.org/10.3390/biom12111640.
Chicago author-date (all authors)
Scott, Emma, Kim De Paepe, and Tom Van de Wiele. 2022. “Postbiotics and Their Health Modulatory Biomolecules.” BIOMOLECULES 12 (11). doi:10.3390/biom12111640.
Vancouver
1.
Scott E, De Paepe K, Van de Wiele T. Postbiotics and their health modulatory biomolecules. BIOMOLECULES. 2022;12(11).
IEEE
[1]
E. Scott, K. De Paepe, and T. Van de Wiele, “Postbiotics and their health modulatory biomolecules,” BIOMOLECULES, vol. 12, no. 11, 2022.
@article{01GQPMN69F9EZCCP44NK7Z5TB8,
  abstract     = {{Postbiotics are a new category of biotics that have the potential to confer health benefits but, unlike probiotics, do not require living cells to induce health effects and thus are not subject to the food safety requirements that apply to live microorganisms. Postbiotics are defined as a "preparation of inanimate microorganisms and/or their components that confers a health benefit on the host". Postbiotic components include short-chain fatty acids, exopolysaccharides, vitamins, teichoic acids, bacteriocins, enzymes and peptides in a non-purified inactivated cell preparation. While research into postbiotics is in its infancy, there is increasing evidence that postbiotics have the potential to modulate human health. Specifically, a number of postbiotics have been shown to improve gut health by strengthening the gut barrier, reducing inflammation and promoting antimicrobial activity against gut pathogens. Additionally, research is being conducted into the potential application of postbiotics to other areas of the body, including the skin, vagina and oral cavity. The purpose of this review is to set out the current research on postbiotics, demonstrate how postbiotics are currently used in commercial products and identify a number of knowledge gaps where further research is needed to identify the potential for future applications of postbiotics.}},
  articleno    = {{1640}},
  author       = {{Scott, Emma and De Paepe, Kim and Van de Wiele, Tom}},
  issn         = {{2218-273X}},
  journal      = {{BIOMOLECULES}},
  keywords     = {{postbiotics,gut health,epithelial barrier,microbiome,exopolysaccharides,bacteriocins,SCFAs,butyrate,antioxidant}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{17}},
  title        = {{Postbiotics and their health modulatory biomolecules}},
  url          = {{http://doi.org/10.3390/biom12111640}},
  volume       = {{12}},
  year         = {{2022}},
}

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