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All-natural oil-filled microcapsules from water-insoluble proteins

(2014) ADVANCED FUNCTIONAL MATERIALS. 24(38). p.5962-5968
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Abstract
The formation and characterization of a novel class of all-natural digestible microcapsules containing a liquid lipid core encapsulated by a water-insoluble protein shell with tunable thickness is demonstrated. As an example of a water-insoluble protein, zein is used—the protein of corn—which is an attractive biomaterial from a sustainable source. The microcapsules are prepared by a direct and simple method, based on the precipitation of protein from the continuous phase of an oil-in-(water/ethanol) emulsion onto the oil droplets without the need of any surfactant. The shell thickness can be controlled by the amount of precipitated protein. An in vitro digestion assay is performed to study the lipid hydrolysis and biodegradability. The rate of lipid hydrolysis and release of fatty acids are highly dependent on the protein shell thickness. All-natural edible microcapsules with controlled degradation under gastrointestinal conditions can enable new applications for oral delivery systems. They may further be used as a model system for controlled release studies of lipophilic compounds and could promote the sustainable use of underutilized water insoluble proteins as functional biomaterials.
Keywords
microcapsules, bipolymers, zein, INTERNAL PHASE-SEPARATION, SHELL MICROCAPSULES, CORE MICROCAPSULES, EMULSION DROPLETS, ZEIN MICROSPHERES, DRUG-DELIVERY, FISH-OIL, MICROENCAPSULATION, ENCAPSULATION, PARTICLES

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Citation

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MLA
Filippidi, Emmanouela, et al. “All-Natural Oil-Filled Microcapsules from Water-Insoluble Proteins.” ADVANCED FUNCTIONAL MATERIALS, vol. 24, no. 38, 2014, pp. 5962–68, doi:10.1002/adfm.201400359.
APA
Filippidi, E., Patel, A., Bouwens, E. C., Voudouris, P., & Velikov, K. P. (2014). All-natural oil-filled microcapsules from water-insoluble proteins. ADVANCED FUNCTIONAL MATERIALS, 24(38), 5962–5968. https://doi.org/10.1002/adfm.201400359
Chicago author-date
Filippidi, Emmanouela, Ashok Patel, Elisabeth CM Bouwens, Panayiotis Voudouris, and Krassimir P Velikov. 2014. “All-Natural Oil-Filled Microcapsules from Water-Insoluble Proteins.” ADVANCED FUNCTIONAL MATERIALS 24 (38): 5962–68. https://doi.org/10.1002/adfm.201400359.
Chicago author-date (all authors)
Filippidi, Emmanouela, Ashok Patel, Elisabeth CM Bouwens, Panayiotis Voudouris, and Krassimir P Velikov. 2014. “All-Natural Oil-Filled Microcapsules from Water-Insoluble Proteins.” ADVANCED FUNCTIONAL MATERIALS 24 (38): 5962–5968. doi:10.1002/adfm.201400359.
Vancouver
1.
Filippidi E, Patel A, Bouwens EC, Voudouris P, Velikov KP. All-natural oil-filled microcapsules from water-insoluble proteins. ADVANCED FUNCTIONAL MATERIALS. 2014;24(38):5962–8.
IEEE
[1]
E. Filippidi, A. Patel, E. C. Bouwens, P. Voudouris, and K. P. Velikov, “All-natural oil-filled microcapsules from water-insoluble proteins,” ADVANCED FUNCTIONAL MATERIALS, vol. 24, no. 38, pp. 5962–5968, 2014.
@article{5709025,
  abstract     = {{The formation and characterization of a novel class of all-natural digestible microcapsules containing a liquid lipid core encapsulated by a water-insoluble protein shell with tunable thickness is demonstrated. As an example of a water-insoluble protein, zein is used—the protein of corn—which is an attractive biomaterial from a sustainable source. The microcapsules are prepared by a direct and simple method, based on the precipitation of protein from the continuous phase of an oil-in-(water/ethanol) emulsion onto the oil droplets without the need of any surfactant. The shell thickness can be controlled by the amount of precipitated protein. An in vitro digestion assay is performed to study the lipid hydrolysis and biodegradability. The rate of lipid hydrolysis and release of fatty acids are highly dependent on the protein shell thickness. All-natural edible microcapsules with controlled degradation under gastrointestinal conditions can enable new applications for oral delivery systems. They may further be used as a model system for controlled release studies of lipophilic compounds and could promote the sustainable use of underutilized water insoluble proteins as functional biomaterials.}},
  author       = {{Filippidi, Emmanouela and Patel, Ashok and Bouwens, Elisabeth CM and Voudouris, Panayiotis and Velikov, Krassimir P}},
  issn         = {{1616-301X}},
  journal      = {{ADVANCED FUNCTIONAL MATERIALS}},
  keywords     = {{microcapsules,bipolymers,zein,INTERNAL PHASE-SEPARATION,SHELL MICROCAPSULES,CORE MICROCAPSULES,EMULSION DROPLETS,ZEIN MICROSPHERES,DRUG-DELIVERY,FISH-OIL,MICROENCAPSULATION,ENCAPSULATION,PARTICLES}},
  language     = {{eng}},
  number       = {{38}},
  pages        = {{5962--5968}},
  title        = {{All-natural oil-filled microcapsules from water-insoluble proteins}},
  url          = {{http://doi.org/10.1002/adfm.201400359}},
  volume       = {{24}},
  year         = {{2014}},
}

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