SENATOR: a novel software approach to prescribing optimisation in older people with multimorbidity
- Author
- Denis O'Mahony, Aidan Holly, Antonio Cherubini, Alfonso Cruz-Jentoft, Mirko Petrovic (UGent) , Roy Soiza, Adelsteinn Gudmundsson, Joseph Eustace, Paul Gallagher, Anna Birna Almarsdottir, Ric Fordham and Otilia Postea
- Organization
- Abstract
- Background: The challenges of prescribing optimisation in the growing population of multi-morbid older people with complex polypharmacy are considerable. Since most people who prescribe medication for multi-morbid older patients do not have specific training or expertise in medication optimisation or complex polypharmacy, there is a need for a novel, systematic and reliable solution to address this challenge. Methods: In 2012, the SENATOR consortium (www.senator-project.eu) was funded under the EU’s FP7 programme to design and test by clinical trial a software engine specifically designed for drug/nondrug treatment optimisation in older people with multi-morbidity and associated complex polypharmacy. In partnership with a healthcare software SME , the SENATOR consortium has developed a software engine for this purpose. The consortium has also embarked on a randomised clinical trial (RCT) comparing the effects of SENATOR softwareguided prescribing optimisation in older multi-morbid patients hospitalised with acute illness with standard pharmaceutical care in 6 European centres, randomised into two groups of approximately 900 patients each. Outcome measures: The primary outcome measure is the proportion of patients experiencing one or more non-trivial ADR’s during their index hospitalisation. Other outcome measures include medication appropriateness, all-cause in-patient mortality, cost of composite healthcare utilization and quality of life at 12 weeks follow-up. The SENATOR RCT will be completed in 2017. Conclusions: The SENATOR software tool is designed to curtail polypharmacy, inappropriate prescribing and prevent non-trivial adverse drug reactions/events. The SENATOR RCT will determine its efficacy in acutely ill older multi-morbid patients cared for by clinicians other than geriatricians.
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-6928857
- MLA
- O’Mahony, Denis, et al. “SENATOR: A Novel Software Approach to Prescribing Optimisation in Older People with Multimorbidity.” IRISH AGEING STUDIES REVIEW, vol. 6, no. 1, 2015, pp. 118–19.
- APA
- O’Mahony, D., Holly, A., Cherubini, A., Cruz-Jentoft, A., Petrovic, M., Soiza, R., … Postea, O. (2015). SENATOR: a novel software approach to prescribing optimisation in older people with multimorbidity. IRISH AGEING STUDIES REVIEW, 6(1), 118–119.
- Chicago author-date
- O’Mahony, Denis, Aidan Holly, Antonio Cherubini, Alfonso Cruz-Jentoft, Mirko Petrovic, Roy Soiza, Adelsteinn Gudmundsson, et al. 2015. “SENATOR: A Novel Software Approach to Prescribing Optimisation in Older People with Multimorbidity.” In IRISH AGEING STUDIES REVIEW, 6:118–19.
- Chicago author-date (all authors)
- O’Mahony, Denis, Aidan Holly, Antonio Cherubini, Alfonso Cruz-Jentoft, Mirko Petrovic, Roy Soiza, Adelsteinn Gudmundsson, Joseph Eustace, Paul Gallagher, Anna Birna Almarsdottir, Ric Fordham, and Otilia Postea. 2015. “SENATOR: A Novel Software Approach to Prescribing Optimisation in Older People with Multimorbidity.” In IRISH AGEING STUDIES REVIEW, 6:118–119.
- Vancouver
- 1.O’Mahony D, Holly A, Cherubini A, Cruz-Jentoft A, Petrovic M, Soiza R, et al. SENATOR: a novel software approach to prescribing optimisation in older people with multimorbidity. In: IRISH AGEING STUDIES REVIEW. 2015. p. 118–9.
- IEEE
- [1]D. O’Mahony et al., “SENATOR: a novel software approach to prescribing optimisation in older people with multimorbidity,” in IRISH AGEING STUDIES REVIEW, Dublin, Ireland, 2015, vol. 6, no. 1, pp. 118–119.
@inproceedings{6928857, abstract = {{Background: The challenges of prescribing optimisation in the growing population of multi-morbid older people with complex polypharmacy are considerable. Since most people who prescribe medication for multi-morbid older patients do not have specific training or expertise in medication optimisation or complex polypharmacy, there is a need for a novel, systematic and reliable solution to address this challenge. Methods: In 2012, the SENATOR consortium (www.senator-project.eu) was funded under the EU’s FP7 programme to design and test by clinical trial a software engine specifically designed for drug/nondrug treatment optimisation in older people with multi-morbidity and associated complex polypharmacy. In partnership with a healthcare software SME , the SENATOR consortium has developed a software engine for this purpose. The consortium has also embarked on a randomised clinical trial (RCT) comparing the effects of SENATOR softwareguided prescribing optimisation in older multi-morbid patients hospitalised with acute illness with standard pharmaceutical care in 6 European centres, randomised into two groups of approximately 900 patients each. Outcome measures: The primary outcome measure is the proportion of patients experiencing one or more non-trivial ADR’s during their index hospitalisation. Other outcome measures include medication appropriateness, all-cause in-patient mortality, cost of composite healthcare utilization and quality of life at 12 weeks follow-up. The SENATOR RCT will be completed in 2017. Conclusions: The SENATOR software tool is designed to curtail polypharmacy, inappropriate prescribing and prevent non-trivial adverse drug reactions/events. The SENATOR RCT will determine its efficacy in acutely ill older multi-morbid patients cared for by clinicians other than geriatricians.}}, author = {{O'Mahony, Denis and Holly, Aidan and Cherubini, Antonio and Cruz-Jentoft, Alfonso and Petrovic, Mirko and Soiza, Roy and Gudmundsson, Adelsteinn and Eustace, Joseph and Gallagher, Paul and Almarsdottir, Anna Birna and Fordham, Ric and Postea, Otilia}}, booktitle = {{IRISH AGEING STUDIES REVIEW}}, issn = {{1649-9972}}, language = {{eng}}, location = {{Dublin, Ireland}}, number = {{1}}, pages = {{118--119}}, title = {{SENATOR: a novel software approach to prescribing optimisation in older people with multimorbidity}}, volume = {{6}}, year = {{2015}}, }