Fabrication of PEOT/PBT nanofibers by atmospheric pressure plasma jet treatment of electrospinning solutions for tissue engineering
- Author
- Silvia Grande, Pieter Cools (UGent) , Mahtab Asadian (UGent) , Joachim Van Guyse, Yuliia Onyshchenko (UGent) , Heidi Declercq (UGent) , Rino Morent (UGent) , Richard Hoogenboom (UGent) and Nathalie De Geyter (UGent)
- Organization
- Abstract
- This study focuses on the enhanced electrospinning of 300-Polyethylene oxide-polyethylene oxide terephthalate/polybutylene terephthalate (PEOT/PBT). An atmospheric pressure plasma jet for liquid treatment is applied to a solution with 9 w/v% PEOT/PBT dissolved in either chloroform (CHCl3), CHCl3 + N,N-dimethylformamide (DMF), CHCl3 + methanol (MeOH), or CHCl3 + hexafluoroisopropanol (HFIP). For all conditions, the plasma-treated samples present better-quality fibers: less or no-beads and uniform fiber diameter distribution. Except for CHCl3 + DMF, no significant changes to the material bulk are detected, as shown with size exclusion chromatography (SEC). X-ray photoelectron spectroscopy (XPS) spectra performed on nanofibers record an increase in C-C bonds for the CHCl3 + DMF combination upon plasma modification, while a shift and slight increase in oxygen-containing bonds is found for the CHCl3 + HFIP and CHCl3 + MeOH mixtures. MTT assay shows no-cytotoxic effects for CHCl3 + DMF, while a better cellular adhesion is found on nanofibers from CHCl3 + MeOH and CHCl3 + HFIP. Among the examined additives, MeOH is preferable as it produces beadless electrospun nanofibers with an average diameter of 290 +/- 100 nm without causing significant changes to the final nanofiber surface properties.
- Keywords
- atmospheric pressure plasma jet, electrospinning, nanofibers, polyethylene oxide terephthalate/polybutylene terephthalate copolymer, plasma-liquid interactions, FIBER DIAMETER, EPSILON-CAPROLACTONE, COPOLYMERS, IMPROVE, N, N-DIMETHYLFORMAMIDE, PROLIFERATION, POLYACTIVE(R), ARCHITECTURE, TECHNOLOGY, SCAFFOLDS
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8578818
- MLA
- Grande, Silvia, et al. “Fabrication of PEOT/PBT Nanofibers by Atmospheric Pressure Plasma Jet Treatment of Electrospinning Solutions for Tissue Engineering.” MACROMOLECULAR BIOSCIENCE, vol. 18, no. 12, 2018, doi:10.1002/mabi.201800309.
- APA
- Grande, S., Cools, P., Asadian, M., Van Guyse, J., Onyshchenko, Y., Declercq, H., … De Geyter, N. (2018). Fabrication of PEOT/PBT nanofibers by atmospheric pressure plasma jet treatment of electrospinning solutions for tissue engineering. MACROMOLECULAR BIOSCIENCE, 18(12). https://doi.org/10.1002/mabi.201800309
- Chicago author-date
- Grande, Silvia, Pieter Cools, Mahtab Asadian, Joachim Van Guyse, Yuliia Onyshchenko, Heidi Declercq, Rino Morent, Richard Hoogenboom, and Nathalie De Geyter. 2018. “Fabrication of PEOT/PBT Nanofibers by Atmospheric Pressure Plasma Jet Treatment of Electrospinning Solutions for Tissue Engineering.” MACROMOLECULAR BIOSCIENCE 18 (12). https://doi.org/10.1002/mabi.201800309.
- Chicago author-date (all authors)
- Grande, Silvia, Pieter Cools, Mahtab Asadian, Joachim Van Guyse, Yuliia Onyshchenko, Heidi Declercq, Rino Morent, Richard Hoogenboom, and Nathalie De Geyter. 2018. “Fabrication of PEOT/PBT Nanofibers by Atmospheric Pressure Plasma Jet Treatment of Electrospinning Solutions for Tissue Engineering.” MACROMOLECULAR BIOSCIENCE 18 (12). doi:10.1002/mabi.201800309.
- Vancouver
- 1.Grande S, Cools P, Asadian M, Van Guyse J, Onyshchenko Y, Declercq H, et al. Fabrication of PEOT/PBT nanofibers by atmospheric pressure plasma jet treatment of electrospinning solutions for tissue engineering. MACROMOLECULAR BIOSCIENCE. 2018;18(12).
- IEEE
- [1]S. Grande et al., “Fabrication of PEOT/PBT nanofibers by atmospheric pressure plasma jet treatment of electrospinning solutions for tissue engineering,” MACROMOLECULAR BIOSCIENCE, vol. 18, no. 12, 2018.
@article{8578818, abstract = {{This study focuses on the enhanced electrospinning of 300-Polyethylene oxide-polyethylene oxide terephthalate/polybutylene terephthalate (PEOT/PBT). An atmospheric pressure plasma jet for liquid treatment is applied to a solution with 9 w/v% PEOT/PBT dissolved in either chloroform (CHCl3), CHCl3 + N,N-dimethylformamide (DMF), CHCl3 + methanol (MeOH), or CHCl3 + hexafluoroisopropanol (HFIP). For all conditions, the plasma-treated samples present better-quality fibers: less or no-beads and uniform fiber diameter distribution. Except for CHCl3 + DMF, no significant changes to the material bulk are detected, as shown with size exclusion chromatography (SEC). X-ray photoelectron spectroscopy (XPS) spectra performed on nanofibers record an increase in C-C bonds for the CHCl3 + DMF combination upon plasma modification, while a shift and slight increase in oxygen-containing bonds is found for the CHCl3 + HFIP and CHCl3 + MeOH mixtures. MTT assay shows no-cytotoxic effects for CHCl3 + DMF, while a better cellular adhesion is found on nanofibers from CHCl3 + MeOH and CHCl3 + HFIP. Among the examined additives, MeOH is preferable as it produces beadless electrospun nanofibers with an average diameter of 290 +/- 100 nm without causing significant changes to the final nanofiber surface properties.}}, articleno = {{1800309}}, author = {{Grande, Silvia and Cools, Pieter and Asadian, Mahtab and Van Guyse, Joachim and Onyshchenko, Yuliia and Declercq, Heidi and Morent, Rino and Hoogenboom, Richard and De Geyter, Nathalie}}, issn = {{1616-5187}}, journal = {{MACROMOLECULAR BIOSCIENCE}}, keywords = {{atmospheric pressure plasma jet,electrospinning,nanofibers,polyethylene oxide terephthalate/polybutylene terephthalate copolymer,plasma-liquid interactions,FIBER DIAMETER,EPSILON-CAPROLACTONE,COPOLYMERS,IMPROVE,N,N-DIMETHYLFORMAMIDE,PROLIFERATION,POLYACTIVE(R),ARCHITECTURE,TECHNOLOGY,SCAFFOLDS}}, language = {{eng}}, number = {{12}}, pages = {{17}}, title = {{Fabrication of PEOT/PBT nanofibers by atmospheric pressure plasma jet treatment of electrospinning solutions for tissue engineering}}, url = {{http://doi.org/10.1002/mabi.201800309}}, volume = {{18}}, year = {{2018}}, }
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