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Purified and specific cytoplasmic pollen extract : a non-hormonal alternative for the treatment of menopausal symptoms

Andrea Genazzani, Nick Panay, Tommaso Simoncini, Herman Depypere (UGent) , Alfred Mueck, Christian Egarter, Nicoletta Biglia, Tomas Fait, Martin Birkhaeuser, Sven O. Skouby, et al.
(2020) GYNECOLOGICAL ENDOCRINOLOGY. 36(3). p.190-196
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Organization
Abstract
Research into non-hormonal, alternative therapies is necessary for women for whom menopausal hormone therapy is contraindicated or for women who do not wish to take hormones. This review focuses on one such non-hormonal option, namely, purified and specific cytoplasmic pollen extract, or PureCyTonin (R). This extract has been evaluated in several preclinical and clinical studies, where it demonstrated its value as a safe and non-estrogenic alternative for menopause. This review presents the beneficial effects of PureCyTonin (R) in the treatment of menopausal symptoms (e.g. hot flushes) in healthy women, as well as in premenstrual syndrome. We discuss the mechanism of action of PureCyTonin (R), an SSRI-'like' therapy. The lack of estrogenic effect demonstrated in preclinical studies suggests that PureCyTonin (R) may also be a suitable option for the management of menopausal symptoms in women with breast cancer.
Keywords
QUALITY-OF-LIFE, VASOMOTOR SYMPTOMS, PREMENSTRUAL-SYNDROME, HOT FLUSHES, WOMEN, MANAGEMENT, EFFICACY, SEROTONIN, PARALLEL, Purified and specific cytoplasmic pollen extract, PureCyTonin (R), menopause, non-hormonal alternative, hot flushes, premenstrual syndrome, Serelys (R)

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MLA
Genazzani, Andrea, et al. “Purified and Specific Cytoplasmic Pollen Extract : A Non-Hormonal Alternative for the Treatment of Menopausal Symptoms.” GYNECOLOGICAL ENDOCRINOLOGY, vol. 36, no. 3, 2020, pp. 190–96, doi:10.1080/09513590.2020.1722994.
APA
Genazzani, A., Panay, N., Simoncini, T., Depypere, H., Mueck, A., Egarter, C., … Palacios, S. (2020). Purified and specific cytoplasmic pollen extract : a non-hormonal alternative for the treatment of menopausal symptoms. GYNECOLOGICAL ENDOCRINOLOGY, 36(3), 190–196. https://doi.org/10.1080/09513590.2020.1722994
Chicago author-date
Genazzani, Andrea, Nick Panay, Tommaso Simoncini, Herman Depypere, Alfred Mueck, Christian Egarter, Nicoletta Biglia, et al. 2020. “Purified and Specific Cytoplasmic Pollen Extract : A Non-Hormonal Alternative for the Treatment of Menopausal Symptoms.” GYNECOLOGICAL ENDOCRINOLOGY 36 (3): 190–96. https://doi.org/10.1080/09513590.2020.1722994.
Chicago author-date (all authors)
Genazzani, Andrea, Nick Panay, Tommaso Simoncini, Herman Depypere, Alfred Mueck, Christian Egarter, Nicoletta Biglia, Tomas Fait, Martin Birkhaeuser, Sven O. Skouby, Mark Brincat, Steven Goldstein, Xiangyan Ruan, Cuauhtemoc Celis-Gonzales, and Santiago Palacios. 2020. “Purified and Specific Cytoplasmic Pollen Extract : A Non-Hormonal Alternative for the Treatment of Menopausal Symptoms.” GYNECOLOGICAL ENDOCRINOLOGY 36 (3): 190–196. doi:10.1080/09513590.2020.1722994.
Vancouver
1.
Genazzani A, Panay N, Simoncini T, Depypere H, Mueck A, Egarter C, et al. Purified and specific cytoplasmic pollen extract : a non-hormonal alternative for the treatment of menopausal symptoms. GYNECOLOGICAL ENDOCRINOLOGY. 2020;36(3):190–6.
IEEE
[1]
A. Genazzani et al., “Purified and specific cytoplasmic pollen extract : a non-hormonal alternative for the treatment of menopausal symptoms,” GYNECOLOGICAL ENDOCRINOLOGY, vol. 36, no. 3, pp. 190–196, 2020.
@article{8694589,
  abstract     = {{Research into non-hormonal, alternative therapies is necessary for women for whom menopausal hormone therapy is contraindicated or for women who do not wish to take hormones. This review focuses on one such non-hormonal option, namely, purified and specific cytoplasmic pollen extract, or PureCyTonin (R). This extract has been evaluated in several preclinical and clinical studies, where it demonstrated its value as a safe and non-estrogenic alternative for menopause. This review presents the beneficial effects of PureCyTonin (R) in the treatment of menopausal symptoms (e.g. hot flushes) in healthy women, as well as in premenstrual syndrome. We discuss the mechanism of action of PureCyTonin (R), an SSRI-'like' therapy. The lack of estrogenic effect demonstrated in preclinical studies suggests that PureCyTonin (R) may also be a suitable option for the management of menopausal symptoms in women with breast cancer.}},
  author       = {{Genazzani, Andrea and Panay, Nick and Simoncini, Tommaso and Depypere, Herman and Mueck, Alfred and Egarter, Christian and Biglia, Nicoletta and Fait, Tomas and Birkhaeuser, Martin and Skouby, Sven O. and Brincat, Mark and Goldstein, Steven and Ruan, Xiangyan and Celis-Gonzales, Cuauhtemoc and Palacios, Santiago}},
  issn         = {{0951-3590}},
  journal      = {{GYNECOLOGICAL ENDOCRINOLOGY}},
  keywords     = {{QUALITY-OF-LIFE,VASOMOTOR SYMPTOMS,PREMENSTRUAL-SYNDROME,HOT FLUSHES,WOMEN,MANAGEMENT,EFFICACY,SEROTONIN,PARALLEL,Purified and specific cytoplasmic pollen extract,PureCyTonin (R),menopause,non-hormonal alternative,hot flushes,premenstrual syndrome,Serelys (R)}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{190--196}},
  title        = {{Purified and specific cytoplasmic pollen extract : a non-hormonal alternative for the treatment of menopausal symptoms}},
  url          = {{http://doi.org/10.1080/09513590.2020.1722994}},
  volume       = {{36}},
  year         = {{2020}},
}
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