Circulating non-coding RNAs in head and neck cancer : roles in diagnosis, prognosis, and therapy monitoring
- Author
- Araceli Diez-Fraile, Joke De Ceulaer, Charlotte Derpoorter (UGent) , Christophe Spaas, Tom De Backer, Philippe Lamoral, Johan Abeloos and Tim Lammens (UGent)
- Organization
- Abstract
- Head and neck cancer (HNC), the seventh most common form of cancer worldwide, is a group of epithelial malignancies affecting sites in the upper aerodigestive tract. The 5-year overall survival for patients with HNC has stayed around 40-50% for decades, with mortality being attributable mainly to late diagnosis and recurrence. Recently, non-coding RNAs, including tRNA halves, YRNA fragments, microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), have been identified in the blood and saliva of patients diagnosed with HNC. These observations have recently fueled the study of their potential use in early detection, diagnosis, and risk assessment. The present review focuses on recent insights and the potential impact that circulating non-coding RNA evaluation may have on clinical decision-making in the management of HNC.
- Keywords
- head and neck cancer, circulating non-coding RNA, liquid biopsy, biomarkers
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8695721
- MLA
- Diez-Fraile, Araceli, et al. “Circulating Non-Coding RNAs in Head and Neck Cancer : Roles in Diagnosis, Prognosis, and Therapy Monitoring.” CELLS, vol. 10, no. 1, 2021, doi:10.3390/cells10010048.
- APA
- Diez-Fraile, A., Ceulaer, J. D., Derpoorter, C., Spaas, C., Backer, T. D., Lamoral, P., … Lammens, T. (2021). Circulating non-coding RNAs in head and neck cancer : roles in diagnosis, prognosis, and therapy monitoring. CELLS, 10(1). https://doi.org/10.3390/cells10010048
- Chicago author-date
- Diez-Fraile, Araceli, Joke De Ceulaer, Charlotte Derpoorter, Christophe Spaas, Tom De Backer, Philippe Lamoral, Johan Abeloos, and Tim Lammens. 2021. “Circulating Non-Coding RNAs in Head and Neck Cancer : Roles in Diagnosis, Prognosis, and Therapy Monitoring.” CELLS 10 (1). https://doi.org/10.3390/cells10010048.
- Chicago author-date (all authors)
- Diez-Fraile, Araceli, Joke De Ceulaer, Charlotte Derpoorter, Christophe Spaas, Tom De Backer, Philippe Lamoral, Johan Abeloos, and Tim Lammens. 2021. “Circulating Non-Coding RNAs in Head and Neck Cancer : Roles in Diagnosis, Prognosis, and Therapy Monitoring.” CELLS 10 (1). doi:10.3390/cells10010048.
- Vancouver
- 1.Diez-Fraile A, Ceulaer JD, Derpoorter C, Spaas C, Backer TD, Lamoral P, et al. Circulating non-coding RNAs in head and neck cancer : roles in diagnosis, prognosis, and therapy monitoring. CELLS. 2021;10(1).
- IEEE
- [1]A. Diez-Fraile et al., “Circulating non-coding RNAs in head and neck cancer : roles in diagnosis, prognosis, and therapy monitoring,” CELLS, vol. 10, no. 1, 2021.
@article{8695721, abstract = {{Head and neck cancer (HNC), the seventh most common form of cancer worldwide, is a group of epithelial malignancies affecting sites in the upper aerodigestive tract. The 5-year overall survival for patients with HNC has stayed around 40-50% for decades, with mortality being attributable mainly to late diagnosis and recurrence. Recently, non-coding RNAs, including tRNA halves, YRNA fragments, microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), have been identified in the blood and saliva of patients diagnosed with HNC. These observations have recently fueled the study of their potential use in early detection, diagnosis, and risk assessment. The present review focuses on recent insights and the potential impact that circulating non-coding RNA evaluation may have on clinical decision-making in the management of HNC.}}, articleno = {{48}}, author = {{Diez-Fraile, Araceli and Ceulaer, Joke De and Derpoorter, Charlotte and Spaas, Christophe and Backer, Tom De and Lamoral, Philippe and Abeloos, Johan and Lammens, Tim}}, issn = {{2073-4409}}, journal = {{CELLS}}, keywords = {{head and neck cancer,circulating non-coding RNA,liquid biopsy,biomarkers}}, language = {{eng}}, number = {{1}}, pages = {{13}}, title = {{Circulating non-coding RNAs in head and neck cancer : roles in diagnosis, prognosis, and therapy monitoring}}, url = {{http://doi.org/10.3390/cells10010048}}, volume = {{10}}, year = {{2021}}, }
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