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Epidemiology of native kidney disease in Flanders : results from the FCGG kidney biopsy registry

(2022) CLINICAL KIDNEY JOURNAL. 15(7). p.1361-1372
Author
Organization
Abstract
Background The Flemish Collaborative Glomerulonephritis Group (FCGG) registry is the first population-based native kidney biopsy registry in Flanders, Belgium. In this first analysis, we report on patient demographics, frequency distribution and incidence rate of biopsied kidney disease in adults in Flanders. Methods From January 2017 to December 2019, a total of 2054 adult first native kidney biopsies were included. A 'double diagnostic coding' strategy was used, in which every biopsy sample received a histopathological and final clinical diagnosis. Frequency distribution and incidence rate of both diagnoses were reported and compared with other European registries. Results The median age at biopsy was 61.1 years (interquartile range, 46.1-71.7); male patients were more prevalent (62.1%) and biopsy incidence rate was 129.3 per million persons per year. Immunoglobulin A nephropathy was the most frequently diagnosed kidney disease (355 biopsies, 17.3% of total) with a similar frequency as in previously published European registries. The frequency of tubulointerstitial nephritis (220 biopsies, 10.7%) and diabetic kidney disease (154 biopsies, 7.5%) was remarkably higher, which may be attributed to changes in disease incidence as well as biopsy practices. Discordances between histopathological and final clinical diagnoses were noted and indicate areas for improvement in diagnostic coding systems. Conclusions The FCGG registry, with its 'double diagnostic coding' strategy, provides useful population-based epidemiological data on a large Western European population and allows subgroup selection for future research.
Keywords
Transplantation, Nephrology, biopsy, epidemiology, incidence, frequency, native kidney, observational, pathology, registry, RENAL BIOPSY, PRIMARY GLOMERULONEPHRITIS, FREQUENCY, DIAGNOSIS, PATHOLOGY

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MLA
Laurens, Wim, et al. “Epidemiology of Native Kidney Disease in Flanders : Results from the FCGG Kidney Biopsy Registry.” CLINICAL KIDNEY JOURNAL, vol. 15, no. 7, 2022, pp. 1361–72, doi:10.1093/ckj/sfac033.
APA
Laurens, W., Deleersnijder, D., Dendooven, A., Lerut, E., De Vriese, A., Dejagere, T., … FCGG collaborative group, [missing]. (2022). Epidemiology of native kidney disease in Flanders : results from the FCGG kidney biopsy registry. CLINICAL KIDNEY JOURNAL, 15(7), 1361–1372. https://doi.org/10.1093/ckj/sfac033
Chicago author-date
Laurens, Wim, Dries Deleersnijder, Amélie Dendooven, Evelyne Lerut, An De Vriese, Tom Dejagere, Mark Helbert, et al. 2022. “Epidemiology of Native Kidney Disease in Flanders : Results from the FCGG Kidney Biopsy Registry.” CLINICAL KIDNEY JOURNAL 15 (7): 1361–72. https://doi.org/10.1093/ckj/sfac033.
Chicago author-date (all authors)
Laurens, Wim, Dries Deleersnijder, Amélie Dendooven, Evelyne Lerut, An De Vriese, Tom Dejagere, Mark Helbert, Rachel Hellemans, Priyanka Koshy, Bart Maes, Lissa Pipeleers, Amaryllis H Van Craenenbroeck, Steven Van Laecke, Johan Vande Walle, Marie M Coutteneye, Johan De Meester, Ben Sprangers, Anja De Rycke, Anne-Marie Bogaert, Annemie Woestenburg, Bart Denys, Domien Peeters, Hilde Vanbelleghem, Jan Donck, Johan Scharpé, Nele De Clippeleir, Joris Vanparys, Karen Meyvis, Kurt Vandepitte, Liza-Maria Reyns, Luc Verresen, Marc Decupere, Miranda Zeegers, Nathalie Neirynck, Pascale Bernaert, Wim Lemahieu, Elena Levtchenko, Sevasti Karamaria, Koen Van Hoeck, Dominique Trouet, Reiner Mauel, Anne Hoorens, Jo Van Dorpe, Marleen Praet, Caroline Geers, Tania Roskams, Selda Aydin, Vasiliki Siozopoulou, Anne-Marie Schelfhout, Hendrik De Raeve, Edwin Steenkiste, Francesca Dedeurwaerdere, Ignace Dalle, Kristof Cokelaere, Stijn Deloose, Pascale De Paepe, Peter Van Eyken, and [missing] FCGG collaborative group. 2022. “Epidemiology of Native Kidney Disease in Flanders : Results from the FCGG Kidney Biopsy Registry.” CLINICAL KIDNEY JOURNAL 15 (7): 1361–1372. doi:10.1093/ckj/sfac033.
Vancouver
1.
Laurens W, Deleersnijder D, Dendooven A, Lerut E, De Vriese A, Dejagere T, et al. Epidemiology of native kidney disease in Flanders : results from the FCGG kidney biopsy registry. CLINICAL KIDNEY JOURNAL. 2022;15(7):1361–72.
IEEE
[1]
W. Laurens et al., “Epidemiology of native kidney disease in Flanders : results from the FCGG kidney biopsy registry,” CLINICAL KIDNEY JOURNAL, vol. 15, no. 7, pp. 1361–1372, 2022.
@article{8738106,
  abstract     = {{Background The Flemish Collaborative Glomerulonephritis Group (FCGG) registry is the first population-based native kidney biopsy registry in Flanders, Belgium. In this first analysis, we report on patient demographics, frequency distribution and incidence rate of biopsied kidney disease in adults in Flanders. Methods From January 2017 to December 2019, a total of 2054 adult first native kidney biopsies were included. A 'double diagnostic coding' strategy was used, in which every biopsy sample received a histopathological and final clinical diagnosis. Frequency distribution and incidence rate of both diagnoses were reported and compared with other European registries. Results The median age at biopsy was 61.1 years (interquartile range, 46.1-71.7); male patients were more prevalent (62.1%) and biopsy incidence rate was 129.3 per million persons per year. Immunoglobulin A nephropathy was the most frequently diagnosed kidney disease (355 biopsies, 17.3% of total) with a similar frequency as in previously published European registries. The frequency of tubulointerstitial nephritis (220 biopsies, 10.7%) and diabetic kidney disease (154 biopsies, 7.5%) was remarkably higher, which may be attributed to changes in disease incidence as well as biopsy practices. Discordances between histopathological and final clinical diagnoses were noted and indicate areas for improvement in diagnostic coding systems. Conclusions The FCGG registry, with its 'double diagnostic coding' strategy, provides useful population-based epidemiological data on a large Western European population and allows subgroup selection for future research.}},
  author       = {{Laurens, Wim and Deleersnijder, Dries and Dendooven, Amélie and Lerut, Evelyne and De Vriese, An and Dejagere, Tom and Helbert, Mark and Hellemans, Rachel and Koshy, Priyanka and Maes, Bart and Pipeleers, Lissa and Van Craenenbroeck, Amaryllis H and Van Laecke, Steven and Vande Walle, Johan and Coutteneye, Marie M and De Meester, Johan and Sprangers, Ben and De Rycke, Anja and Bogaert, Anne-Marie and Woestenburg, Annemie and Denys, Bart and Peeters, Domien and Vanbelleghem, Hilde and Donck, Jan and Scharpé, Johan and De Clippeleir, Nele and Vanparys, Joris and Meyvis, Karen and Vandepitte, Kurt and Reyns, Liza-Maria and Verresen, Luc and Decupere, Marc and Zeegers, Miranda and Neirynck, Nathalie and Bernaert, Pascale and Lemahieu, Wim and Levtchenko, Elena and Karamaria, Sevasti and Van Hoeck, Koen and Trouet, Dominique and Mauel, Reiner and Hoorens, Anne and Van Dorpe, Jo and Praet, Marleen and Geers, Caroline and Roskams, Tania and Aydin, Selda and Siozopoulou, Vasiliki and Schelfhout, Anne-Marie and De Raeve, Hendrik and Steenkiste, Edwin and Dedeurwaerdere, Francesca and Dalle, Ignace and Cokelaere, Kristof and Deloose, Stijn and De Paepe, Pascale and Van Eyken, Peter and FCGG collaborative group, [missing]}},
  issn         = {{2048-8505}},
  journal      = {{CLINICAL KIDNEY JOURNAL}},
  keywords     = {{Transplantation,Nephrology,biopsy,epidemiology,incidence,frequency,native kidney,observational,pathology,registry,RENAL BIOPSY,PRIMARY GLOMERULONEPHRITIS,FREQUENCY,DIAGNOSIS,PATHOLOGY}},
  language     = {{eng}},
  number       = {{7}},
  pages        = {{1361--1372}},
  title        = {{Epidemiology of native kidney disease in Flanders : results from the FCGG kidney biopsy registry}},
  url          = {{http://doi.org/10.1093/ckj/sfac033}},
  volume       = {{15}},
  year         = {{2022}},
}

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