Hemin as a generic and potent protein misfolding inhibitor
-
Altmetric Citations
Liu, Yanqin; Carver, John; Ho, Lam H.; Elias, Abigail K.; Musgrave, Ian F.; Pukala, Tara
Description
Protein misfolding causes serious biological malfunction, resulting in diseases including Alzheimer's disease, Parkinson's disease and cataract. Molecules which inhibit protein misfolding are a promising avenue to explore as therapeutics for the treatment of these diseases. In the present study, thioflavin T fluorescence and transmission electron microscopy experiments demonstrated that hemin prevents amyloid fibril formation of kappa-casein, amyloid beta peptide and α-synuclein by blocking...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2014 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/63814 |
Source: | Biochemical and Biophysical Research Communications |
DOI: | 10.1016/j.bbrc.2014.10.062 |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Liu_Hemin_as_a_generic_and_potent_2014.pdf | 1.36 MB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator