Hormonal Imbalance in Morbidly Obese Bariatric Patients With Liver Steatosis and Non-Alcoholic Steatohepatitis (Nash)
Date
2015
Authors
Abawi, Massih
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Abstract
Non-alcoholic fatty liver disease (NAFLD) is an increasingly common condition affecting about 70% of obese individuals and is now considered a major cause of liver-related morbidity and mortality. NAFLD encompasses a spectrum of hepatic pathologies with excessive accumulation of fat in the liver in patients consuming less than 20 grams of alcohol per day. NAFLD related liver injury ranges from simple hepatic steatosis to more severe forms of the disease including NASH, which can progress to fibrosis, cirrhosis, and ultimately organ failure. There is evidence that causally links NAFLD with imbalance of various hormones, especially these also involved in the development of insulin resistance and obesity.
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Keywords
Biology, Gastric Peptide, Inflammation, Non-Alcoholic Fatty Liver, Obesity, Steatosis, Vitamin D