Turning the tumor microenvironment into a self vaccine site
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Open access via publisher
Authors
Nelson, Delia
Date
2012Type
Journal Article
Metadata
Show full item recordCitation
Nelson, D. 2012. Turning the tumor microenvironment into a self vaccine site. OncoImmunology. 1 (6): pp. 989-991.
Source Title
OncoImmunology
ISSN
School
School of Biomedical Sciences
Collection
Abstract
We aimed to determine if the tumor microenvironment could be turned into a "self"-vaccine site. We show that provoking a local inflammatory response modulates endothelia to permit the infiltration of innate and adaptive effector cells which collaborateto eradicate the inflamed tumor and other tumor deposits, and provide long-term protection. © 2012 Landes Bioscience.
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