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Abstract:

Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods: Sixty-two patients subject to elective open gastrointestinal surgery were evaluated during a period of 22 months. Results: From the initial 62 patients, 2 were excluded, 29 (48.3%) evolved without complications, and 31 (51.6%) with complications. It was observed that the most significant areas under the ROC curve corresponded to BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. MAU was not a discriminating parameter since it did not reach a significant area under the curve (AUC) at any time. Conclusions: The biochemical markers that best relate to the presence of complications are BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. © 2004 The Canadian Society of Clinical Chemists. All rights reserved.

Registro:

Documento: Artículo
Título:Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution
Autor:Bianchi, R.A.; Silva, N.A.; Natal, M.L.; Romero, M.C.
Filiación:Servicio de Cirugía General, Hosp. Gen. Agudos Dr. Cosme Argerich, Gobierno Cd. Auton. de Buenos Aires, Argentina
Laboratorio Central, Hosp. Gen. Agudos Dr. Cosme Argerich, Gobierno Cd. Auton. de Buenos Aires, Argentina
Departamento de Matemática, Fac. de Ciencias Exactas Y Naturales, Universidad de Mar del Plara, Provincia de Buenos Aires, Argentina
Lab. de Analisis Biologicos, Depto. de Quím. Biól., Cd. Autónoma de Buenos Aires, Argentina
Lab. de Analisis Biologicos, Depto. de Quím. Biol., Cd. Autónoma de Buenos Aires, Buenos Aires, Argentina
Palabras clave:Biochemical markers; Postoperative evolution; C reactive protein; lactic acid; adult; aged; article; chemical parameters; controlled study; early diagnosis; female; gastrointestinal surgery; human; major clinical study; male; microalbuminuria; postoperative complication; preoperative evaluation; priority journal; statistical significance; Acid-Base Imbalance; Adult; Aged; Albuminuria; Argentina; Biological Markers; C-Reactive Protein; Creatinine; Digestive System Surgical Procedures; Female; Humans; Lactic Acid; Male; Middle Aged; Postoperative Complications; Postoperative Period; Predictive Value of Tests; Prospective Studies; Systemic Inflammatory Response Syndrome
Año:2004
Volumen:37
Número:5
Página de inicio:404
Página de fin:407
DOI: http://dx.doi.org/10.1016/j.clinbiochem.2003.12.011
Título revista:Clinical Biochemistry
Título revista abreviado:Clin. Biochem.
ISSN:00099120
CODEN:CLBIA
CAS:C reactive protein, 9007-41-4; lactic acid, 113-21-3, 50-21-5; Biological Markers; C-Reactive Protein, 9007-41-4; Creatinine, 60-27-5; Lactic Acid, 50-21-5
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00099120_v37_n5_p404_Bianchi

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Citas:

---------- APA ----------
Bianchi, R.A., Silva, N.A., Natal, M.L. & Romero, M.C. (2004) . Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution. Clinical Biochemistry, 37(5), 404-407.
http://dx.doi.org/10.1016/j.clinbiochem.2003.12.011
---------- CHICAGO ----------
Bianchi, R.A., Silva, N.A., Natal, M.L., Romero, M.C. "Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution" . Clinical Biochemistry 37, no. 5 (2004) : 404-407.
http://dx.doi.org/10.1016/j.clinbiochem.2003.12.011
---------- MLA ----------
Bianchi, R.A., Silva, N.A., Natal, M.L., Romero, M.C. "Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution" . Clinical Biochemistry, vol. 37, no. 5, 2004, pp. 404-407.
http://dx.doi.org/10.1016/j.clinbiochem.2003.12.011
---------- VANCOUVER ----------
Bianchi, R.A., Silva, N.A., Natal, M.L., Romero, M.C. Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution. Clin. Biochem. 2004;37(5):404-407.
http://dx.doi.org/10.1016/j.clinbiochem.2003.12.011