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Abstract:

The development of techniques that allow the precise and efficient edition of the genome of living cells is one of the main goals of biomedical research. Over the last few decades, a number of genome editing tools have been developed, the most prominent being the CRISPR/Cas9 system, a bacterial defense mechanism that has been redesigned for its use in other cellular systems. The accessibility, both technical and economical, and the enormous potential of CRISPR/Cas9 have contributed to an almost unprecedented revolution in the biomedical sciences and represent an important step forward in the field of gene therapy that needs, however, to be taken cautiously.

Registro:

Documento: Artículo
Título:CRISPR/Cas9 and gene therapy
Autor:Giono, L.E.
Filiación:Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), CONICET-Universidad de Buenos AiresBuenos Aires, Argentina
Palabras clave:CRISPR/Cas9; gene therapy; genome editing; human embryos; animal; CRISPR Cas system; gene editing; gene therapy; genetic engineering; genetics; human; RNA editing; Animals; CRISPR-Cas Systems; Gene Editing; Genetic Engineering; Genetic Therapy; Humans; RNA Editing
Año:2017
Volumen:77
Número:5
Página de inicio:405
Página de fin:409
Título revista:Medicina
Título revista abreviado:Medicina (B Aires)
ISSN:00257680
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00257680_v77_n5_p405_Giono

Citas:

---------- APA ----------
(2017) . CRISPR/Cas9 and gene therapy . Medicina, 77(5), 405-409.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00257680_v77_n5_p405_Giono [ ]
---------- CHICAGO ----------
Giono, L.E. "CRISPR/Cas9 and gene therapy " . Medicina 77, no. 5 (2017) : 405-409.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00257680_v77_n5_p405_Giono [ ]
---------- MLA ----------
Giono, L.E. "CRISPR/Cas9 and gene therapy " . Medicina, vol. 77, no. 5, 2017, pp. 405-409.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00257680_v77_n5_p405_Giono [ ]
---------- VANCOUVER ----------
Giono, L.E. CRISPR/Cas9 and gene therapy . Medicina (B Aires). 2017;77(5):405-409.
Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00257680_v77_n5_p405_Giono [ ]