Artículo

Chaufan, G.; Juárez, A.; Basack, S.; Ithuralde, E.; Sabatini, S.E.; Genovese, G.; Oneto, M.L.; Kesten, E.; Ríos de Molina, M.d.C. "Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)" (2006) Toxicology. 227(3):262-270
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Abstract:

The aim of this work was to study the transference of hexachlorobenzene from a green alga (Chlorella kessleri) to an estuary crab (Chasmagnathus granulatus), and to analyze the toxic effects that the xenobiotic has on the latter. The effect of hexachlorobenzene uptake was evaluated measuring oxidative stress, Uroporphyrinogen decarboxylase activity and morphometric parameter alteration, and also performing a histological analysis of crab hepatopancreas. Results demonstrated that hexachlorobenzene enters the alga, is accumulated in it, and then transferred into the crab, causing a decrease in Uroporphyrinogen decarboxylase activity in both organisms. The high malondialdehyde levels detected in crab hepatopancreas after the toxic treatment suggested the existence of hexachlorobenzene-induced lipid peroxidation. Antioxidant defenses such as superoxide dismutase activity and reduced glutathione content fell below normal values on the fourth week of treatment. At the same time, the hepatosomatic index, used as a morphometric parameter, reduced 20% with respect to the control. The histological analysis revealed epithelium disorganization in hepatopancreas tubules, confirming the existence of structural damage caused by hexachlorobenzene. © 2006 Elsevier Ireland Ltd. All rights reserved.

Registro:

Documento: Artículo
Título:Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)
Autor:Chaufan, G.; Juárez, A.; Basack, S.; Ithuralde, E.; Sabatini, S.E.; Genovese, G.; Oneto, M.L.; Kesten, E.; Ríos de Molina, M.d.C.
Filiación:Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pab. 2, Ciudad Autonoma de Buenos Aires 1428, Argentina
Departamento de Biodiversidad y Biología Experimental, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pab. 2, Ciudad Autonoma de Buenos Aires 1428, Argentina
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Av. Rivadavia, 1917 Buenos Aires, Argentina
Palabras clave:Chasmagnathus granulatus; Chlorella kessleri; Hexachlorobenzene; Oxidative stress; Uroporphyrinogen decarboxylase; glutathione; hexachlorobenzene; lipid; malonaldehyde; superoxide dismutase; uroporphyrinogen decarboxylase; animal cell; animal experiment; animal tissue; antioxidant activity; article; bioaccumulation; chasmagnathus granulatus; Chlorella kessleri; controlled study; crab; down regulation; enzyme activity; epithelium; estuary; evaluation; green alga; hepatopancreas; histology; lipid peroxidation; liver injury; male; measurement; morphometrics; nonhuman; oxidative stress; pancreas injury; priority journal; sea pollution; toxicology; transference; Animals; Antioxidants; Brachyura; Chlorella; Epithelium; Food Chain; Glutathione; Hepatopancreas; Hexachlorobenzene; Lipid Peroxidation; Malondialdehyde; Superoxide Dismutase; Tissue Distribution; Xenobiotics; algae; Chasmagnathus granulata; Chlorophyta; Decapoda (Crustacea); Parachlorella kessleri
Año:2006
Volumen:227
Número:3
Página de inicio:262
Página de fin:270
DOI: http://dx.doi.org/10.1016/j.tox.2006.08.011
Título revista:Toxicology
Título revista abreviado:Toxicology
ISSN:0300483X
CODEN:TXCYA
CAS:glutathione, 70-18-8; hexachlorobenzene, 118-74-1, 55600-34-5; lipid, 66455-18-3; malonaldehyde, 542-78-9; superoxide dismutase, 37294-21-6, 9016-01-7, 9054-89-1; uroporphyrinogen decarboxylase, 9024-70-8; Antioxidants; Glutathione, 70-18-8; Hexachlorobenzene, 118-74-1; Malondialdehyde, 542-78-9; Superoxide Dismutase, EC 1.15.1.1; Xenobiotics
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0300483X_v227_n3_p262_Chaufan

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Citas:

---------- APA ----------
Chaufan, G., Juárez, A., Basack, S., Ithuralde, E., Sabatini, S.E., Genovese, G., Oneto, M.L.,..., Ríos de Molina, M.d.C. (2006) . Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus). Toxicology, 227(3), 262-270.
http://dx.doi.org/10.1016/j.tox.2006.08.011
---------- CHICAGO ----------
Chaufan, G., Juárez, A., Basack, S., Ithuralde, E., Sabatini, S.E., Genovese, G., et al. "Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)" . Toxicology 227, no. 3 (2006) : 262-270.
http://dx.doi.org/10.1016/j.tox.2006.08.011
---------- MLA ----------
Chaufan, G., Juárez, A., Basack, S., Ithuralde, E., Sabatini, S.E., Genovese, G., et al. "Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)" . Toxicology, vol. 227, no. 3, 2006, pp. 262-270.
http://dx.doi.org/10.1016/j.tox.2006.08.011
---------- VANCOUVER ----------
Chaufan, G., Juárez, A., Basack, S., Ithuralde, E., Sabatini, S.E., Genovese, G., et al. Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus). Toxicology. 2006;227(3):262-270.
http://dx.doi.org/10.1016/j.tox.2006.08.011