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Referencias:

• Algarra, I., Garcia-Lora, A., Cabrera, T., Ruiz-Cabello, F., Garrido, F., The selection of tumor variants with altered expression of classical and nonclassical MHC class I molecules: Implications for tumor immune escape (2004) Cancer Immunol Immunother, 53, pp. 904-910
• Andre, S., Pieters, R.J., Vrasidas, I., Kaltner, H., Kuwabara, I., Liu, F.T., Liskamp, R.M., Gabius, H.J., Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters, and cell surface glycoconjugates (2001) Chembiochem, 2, pp. 822-830
• Andreola, G., Rivoltini, L., Castelli, C., Huber, V., Perego, P., Deho, P., Squarcina, P., Fais, S., Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles (2002) J Exp Med, 195, pp. 1303-1316
• Bai, X.F., Liu, J.Q., Joshi, P.S., Wang, L., Yin, L., Labanowska, J., Heerema, N., Liu, Y., Different lineages of P1A-expressing cancer cells use divergent modes of immune evasion for T-cell adoptive therapy (2006) Cancer Res, 66, pp. 8241-8249
• Baxevanis, C.N., Papamichail, M., Characterization of the anti-tumor immune response in human cancers and strategies for immunotherapy (1994) Crit Rev Oncol Hematol, 16, pp. 157-179
• Bird, C.H., Sutton, V.R., Sun, J., Hirst, C.E., Novak, A., Kumar, S., Trapani, J.A., Bird, P.I., Selective regulation of apoptosis: The cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway (1998) Mol Cell Biol, 18, pp. 6387-6398
• Biswas, K., Richmond, A., Rayman, P., Biswas, S., Thornton, M., Sa, G., Das, T., Finke, J.H., GM2 expression in renal cell carcinoma: Potential role in tumor-induced T-cell dysfunction (2006) Cancer Res, 66, pp. 6816-6825
• Blank, C., Kuball, J., Voelkl, S., Wiendl, H., Becker, B., Walter, B., Majdic, O., MacKensen, A., Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro (2006) Int J Cancer, 119, pp. 317-327
• Boyland, E., Williams, D.C., The metabolism of tryptophan. 2. the metabolism of tryptophan in patients suffering from cancer of the bladder (1956) Biochem J, 64, pp. 578-582
• Bronte, V., Serafini, P., De Santo, C., Marigo, I., Tosello, V., Mazzoni, A., Segal, D.M., Zanovello, P., IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice (2003) J Immunol, 170, pp. 270-278
• Burnet, F.M., The concept of immunological surveillance (1970) Prog Exp Tumor Res, 13, pp. 1-27
• Cabrera, T., Lara, E., Romero, J.M., Maleno, I., Real, L.M., Ruiz-Cabello, F., Valero, P., Garrido, F., HLA class I expression in metastatic melanoma correlates with tumor development during autologous vaccination (2007) Cancer Immunol Immunother, 56, pp. 709-717
• Cresswell, A.C., Sisley, K., Laws, D., Parsons, M.A., Rennie, I.G., Murray, A.K., Reduced expression of TAP-1 and TAP-2 in posterior uveal melanoma is associated with progression to metastatic disease (2001) Melanoma Res, 11, pp. 275-281
• Curiel, T.J., Coukos, G., Zou, L., Alvarez, X., Cheng, P., Mottram, P., Evdemon-Hogan, M., Zou, W., Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival (2004) Nat Med, 10, pp. 942-949
• Curiel, T.J., Wei, S., Dong, H., Alvarez, X., Cheng, P., Mottram, P., Krzysiek, R., Zou, W., Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity (2003) Nat Med, 9, pp. 562-567
• Chang, C.C., Ogino, T., Mullins, D.W., Oliver, J.L., Yamshchikov, G.V., Bandoh, N., Slingluff Jr., C.L., Ferrone, S., Defective human leukocyte antigen class I-associated antigen presentation caused by a novel beta2-microglobulin loss-of-function in melanoma cells (2006) J Biol Chem, 281, pp. 18763-18773
• Chen, J.J., Sun, Y., Nabel, G.J., Regulation of the proinflammatory effects of Fas ligand (CD95L) (1998) Science, 282, pp. 1714-1717
• Cheng, J., Zhou, T., Liu, C., Shapiro, J.P., Brauer, M.J., Kiefer, M.C., Barr, P.J., Mountz, J.D., Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule (1994) Science, 263, pp. 1759-1762
• Chung, C.D., Patel, V.P., Moran, M., Lewis, L.A., Miceli, M.C., Galectin-1 induces partial TCR zeta-chain phosphorylation and antagonizes processive TCR signal transduction (2000) J Immunol, 165, pp. 3722-3729
• Dalgleish, A., Pandha, H., Tumor antigens as surrogate markers and targets for therapy and vaccines (2007) Adv Cancer Res, 96, pp. 175-190
• Danguy, A., Camby, I., Kiss, R., Galectins and cancer (2002) Biochim Biophys Acta, 1572, pp. 285-293
• Daniel, D., Meyer-Morse, N., Bergsland, E.K., Dehne, K., Coussens, L.M., Hanahan, D., Immune enhancement of skin carcinogenesis by CD4+ T cells (2003) J Exp Med, 197, pp. 1017-1028
• Dannull, J., Su, Z., Rizzieri, D., Yang, B.K., Coleman, D., Yancey, D., Zhang, A., Vieweg, J., Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells (2005) J Clin Invest, 115, pp. 3623-3633
• Daroqui, C.M., Ilarregui, J.M., Rubinstein, N., Salatino, M., Toscano, M.A., Vazquez, P., Bakin, A., Rabinovich, G.A., Regulation of galectin-1 expression by transforming growth factor beta1 in metastatic mammary adenocarcinoma cells: Implications for tumor-immune escape (2007) Cancer Immunol Immunother, 56, pp. 491-499
• De Visser, K.E., Korets, L.V., Coussens, L.M., De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent (2005) Cancer Cell, 7, pp. 411-423
• Demanet, C., Mulder, A., Deneys, V., Worsham, M.J., Maes, P., Claas, F.H., Ferrone, S., Down-regulation of HLA-A and HLA-Bw6, but not HLA-Bw4, allospecificities in leukemic cells: An escape mechanism from CTL and NK attack? (2004) Blood, 103, pp. 3122-3130
• Demetriou, M., Granovsky, M., Quaggin, S., Dennis, J.W., Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation (2001) Nature, 409, pp. 733-739
• Dong, H., Strome, S.E., Salomao, D.R., Tamura, H., Hirano, F., Flies, D.B., Roche, P.C., Chen, L., Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion (2002) Nat Med, 8, pp. 793-800
• Drake, C.G., Jaffee, E., Pardoll, D.M., Mechanisms of immune evasion by tumors (2006) Adv Immunol, 90, pp. 51-81
• Dudley, M.E., Rosenberg, S.A., Adoptive-cell-transfer therapy for the treatment of patients with cancer (2003) Nat Rev Cancer, 3, pp. 666-675
• Dunn, G.P., Old, L.J., Schreiber, R.D., The immunobiology of cancer immunosurveillance and immunoediting (2004) Immunity, 21, pp. 137-148
• Erlich, P., Ueber den jetzigen (1909) Stand der Karzinomforschung Ned Tijdschr Geneeskd, 5, pp. 273-290
• Findley, H.W., Gu, L., Yeager, A.M., Zhou, M., Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia (1997) Blood, 89, pp. 2986-2993
• Frydecka, I., Kosmaczewska, A., Bocko, D., Ciszak, L., Wolowiec, D., Kuliczkowski, K., Kochanowska, I., Alterations of the expression of T-cell-related costimulatory CD28 and downregulatory CD152 (CTLA-4) molecules in patients with B-cell chronic lymphocytic leukaemia (2004) Br J Cancer, 90, pp. 2042-2048
• Fukumori, T., Takenaka, Y., Yoshii, T., Kim, H.R., Hogan, V., Inohara, H., Kagawa, S., Raz, A., CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis (2003) Cancer Res, 63, pp. 8302-8311
• Gabrilovich, D.I., Chen, H.L., Girgis, K.R., Cunningham, H.T., Meny, G.M., Nadaf, S., Kavanaugh, D., Carbone, D.P., Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells [published erratum appears in Nat Med 1996 Nov;2(11):1267] (1996) Nat Med, 2, pp. 1096-1103
• Gabrilovich, D.I., Velders, M.P., Sotomayor, E.M., Kast, W.M., Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells (2001) J Immunol, 166, pp. 5398-5406
• Garcia-Lora, A., Algarra, I., Garrido, F., MHC class I antigens, immune surveillance, and tumor immune escape (2003) J Cell Physiol, 195, pp. 346-355
• Garin, M.I., Chu, C.C., Golshayan, D., Cernuda-Morollon, E., Wait, R., Lechler, R.I., Galectin-1: A key effector of regulation mediated by CD4+CD25+ T cells (2007) Blood, 109, pp. 2058-2065
• Gastman, B.R., Johnson, D.E., Whiteside, T.L., Rabinowich, H., Tumor-induced apoptosis of T lymphocytes: Elucidation of intracellular apoptotic events (2000) Blood, 95, pp. 2015-2023
• Hahn, H.P., Pang, M., He, J., Hernandez, J.D., Yang, R.Y., Li, L.Y., Wang, X., Baum, L.G., Galectin-1 induces nuclear translocation of endonuclease G in caspase- and cytochrome c-independent T cell death (2004) Cell Death Differ, 11, pp. 1277-1286
• Hallermalm, K., De Geer, A., Kiessling, R., Levitsky, V., Levitskaya, J., Autocrine secretion of Fas ligand shields tumor cells from Fas-mediated killing by cytotoxic lymphocytes (2004) Cancer Res, 64, pp. 6775-6782
• Heitger, A., Ladisch, S., Gangliosides block antigen presentation by human monocytes (1996) Biochim Biophys Acta, 1303, pp. 161-168
• Hodi, F.S., Mihm, M.C., Soiffer, R.J., Haluska, F.G., Butler, M., Seiden, M.V., Davis, T., Dranoff, G., Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients (2003) Proc Natl Acad Sci USA, 100, pp. 4712-4717
• Igney, F.H., Behrens, C.K., Krammer, P.H., CD95L mediates tumor counterattack in vitro but induces neutrophil-independent tumor rejection in vivo (2005) Int J Cancer, 113, pp. 78-87
• Igney, F.H., Krammer, P.H., Immune escape of tumors: Apoptosis resistance and tumor counterattack (2002) J Leukoc Biol, 71, pp. 907-920
• Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., Bodmer, J.L., Tschopp, J., Inhibition of death receptor signals by cellular FLIP (1997) Nature, 388, pp. 190-195
• Iwabuchi, K., Yamamura, S., Prinetti, A., Handa, K., Hakomori, S., GM3-enriched microdomain involved in cell adhesion and signal transduction through carbohydrate-carbohydrate interaction in mouse melanoma B16 cells (1998) J Biol Chem, 273, pp. 9130-9138
• Jain, R., Teidier, B.A., Physiological resistance to the treatment of solid tumors (1993) Drug Resistance in Oncology, pp. 87-105. , Dekker New York
• Jessup, J.M., Samara, R., Battle, P., Laguinge, L.M., Carcinoembryonic antigen promotes tumor cell survival in liver through an IL-10-dependent pathway (2004) Clin Exp Metastasis, 21, pp. 709-717
• Jimenez, P., Canton, J., Collado, A., Cabrera, T., Serrano, A., Real, L.M., Garcia, A., Garrido, F., Chromosome loss is the most frequent mechanism contributing to HLA haplotype loss in human tumors (1999) Int J Cancer, 83, pp. 91-97
• Jung, E.J., Moon, H.G., Cho, B.I., Jeong, C.Y., Joo, Y.T., Lee, Y.J., Hong, S.C., Park, S.T., Galectin-1 expression in cancer-associated stromal cells correlates tumor invasiveness and tumor progression in breast cancer (2007) Int J Cancer, 120, pp. 2331-2338
• Kageshita, T., Ishihara, T., Campoli, M., Ferrone, S., Selective monomorphic and polymorphic HLA class I antigenic determinant loss in surgically removed melanoma lesions (2005) Tissue Antigens, 65, pp. 419-428
• Kidd, P., Th1/Th2 balance: The hypothesis, its limitations, and implications for health and disease (2003) Altern Med Rev, 8, pp. 223-246
• Kiessling, R., Wasserman, K., Horiguchi, S., Kono, K., Sjoberg, J., Pisa, P., Petersson, M., Tumor-induced immune dysfunction (1999) Cancer Immunol Immunother, 48, pp. 353-362
• Knutson, K.L., Disis, M.L., Salazar, L.G., CD4 regulatory T cells in human cancer pathogenesis (2007) Cancer Immunol Immunother, 56, pp. 271-285
• Kono, K., Salazar-Onfray, F., Petersson, M., Hansson, J., Masucci, G., Wasserman, K., Nakazawa, T., Kiessling, R., Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity (1996) Eur J Immunol, 26, pp. 1308-1313
• Korman, A.J., Peggs, K.S., Allison, J.P., Checkpoint blockade in cancer immunotherapy (2006) Adv Immunol, 90, pp. 297-339
• Kortylewski, M., Kujawski, M., Wang, T., Wei, S., Zhang, S., Pilon-Thomas, S., Niu, G., Yu, H., Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity (2005) Nat Med, 11, pp. 1314-1321
• Krueger, A., Baumann, S., Krammer, P.H., Kirchhoff, S., FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis (2001) Mol Cell Biol, 21, pp. 8247-8254
• Kryczek, I., Zou, L., Rodriguez, P., Zhu, G., Wei, S., Mottram, P., Brumlik, M., Zou, W., B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma (2006) J Exp Med, 203, pp. 871-881
• Kurnick, J.T., Ramirez-Montagut, T., Boyle, L.A., Andrews, D.M., Pandolfi, F., Durda, P.J., Butera, D., Van Den Elsen, P.J., A novel autocrine pathway of tumor escape from immune recognition: Melanoma cell lines produce a soluble protein that diminishes expression of the gene encoding the melanocyte lineage melan-A/MART-1 antigen through down-modulation of its promoter (2001) J Immunol, 167, pp. 1204-1211
• Kusmartsev, S., Gabrilovich, D.I., Role of immature myeloid cells in mechanisms of immune evasion in cancer (2006) Cancer Immunol Immunother, 55, pp. 237-45
• Langowski, J.L., Zhang, X., Wu, L., Mattson, J.D., Chen, T., Smith, K., Basham, B., Oft, M., IL-23 promotes tumour incidence and growth (2006) Nature, 442, pp. 461-465
• Le, Q.T., Shi, G., Cao, H., Nelson, D.W., Wang, Y., Chen, E.Y., Zhao, S., Koong, A.C., Galectin-1: A link between tumor hypoxia and tumor immune privilege (2005) J Clin Oncol, 23, pp. 8932-8941
• Leach, D.R., Krummel, M.F., Allison, J.P., Enhancement of antitumor immunity by CTLA-4 blockade (1996) Science, 271, pp. 1734-1736
• Liu, F., Rabinovich, G., Galectins as modulators of tumourprogression. (2005) Nat Rev Cancer, 5, pp. 29-41. , 1
• Liyanage, U.K., Moore, T.T., Joo, H.G., Tanaka, Y., Herrmann, V., Doherty, G., Drebin, J.A., Linehan, D.C., Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma (2002) J Immunol, 169, pp. 2756-2761
• Luo, J.L., Maeda, S., Hsu, L.C., Yagita, H., Karin, M., Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression (2004) Cancer Cell, 6, pp. 297-305
• Marincola, F.M., Jaffee, E.M., Hicklin, D.J., Ferrone, S., Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance (2000) Adv Immunol, 74, pp. 181-273
• Matar, P., Rozados, V.R., Gervasoni, S.I., Scharovsky, G.O., Th2/Th1 switch induced by a single low dose of cyclophosphamide in a rat metastatic lymphoma model (2002) Cancer Immunol Immunother, 50, pp. 588-596
• Matar, P., Rozados, V.R., Gervasoni, S.I., Scharovsky, O.G., Down regulation of T-cell-derived IL-10 production by low-dose cyclophosphamide treatment in tumor-bearing rats restores in vitro normal lymphoproliferative response (2001) Int Immunopharmacol, 1, pp. 307-319
• Matar, P., Rozados, V.R., Gonzalez, A.D., Dlugovitzky, D.G., Bonfil, R.D., Scharovsky, O.G., Mechanism of antimetastatic immunopotentiation by low-dose cyclophosphamide (2000) Eur J Cancer, 36, pp. 1060-1066
• Matarrese, P., Tinari, A., Mormone, E., Bianco, G.A., Toscano, M.A., Ascione, B., Rabinovich, G.A., Malorni, W., Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding and fission. (2004) J Biol Chem, 280, pp. 6969-6985. , 8
• Matsuda, M., Petersson, M., Lenkei, R., Taupin, J.L., Magnusson, I., Mellstedt, H., Anderson, P., Kiessling, R., Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: Correlation with the stage of the disease (1995) Int J Cancer, 61, pp. 765-772
• Medema, J.P., De Jong, J., Peltenburg, L.T., Verdegaal, E.M., Gorter, A., Bres, S.A., Franken, K.L., Offringa, R., Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors (2001) Proc Natl Acad Sci USA, 98, pp. 11515-11520
• Miwa, K., Asano, M., Horai, R., Iwakura, Y., Nagata, S., Suda, T., Caspase 1-independent IL-1beta release and inflammation induced by the apoptosis inducer Fas ligand (1998) Nat Med, 4, pp. 1287-1292
• Mizoguchi, H., O'Shea, J.J., Longo, D.L., Loeffler, C.M., McVicar, D.W., Ochoa, A.C., Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice (1992) Science, 258, pp. 1795-1798
• Mor, F., Quintana, F.J., Cohen, I.R., Angiogenesis-inflammation cross-talk: Vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization (2004) J Immunol, 172, pp. 4618-4623
• Muller, A.J., Duhadaway, J.B., Donover, P.S., Sutanto-Ward, E., Prendergast, G.C., Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy (2005) Nat Med, 11, pp. 312-329
• Munn, D.H., Indoleamine 2,3-dioxygenase, tumor-induced tolerance and counter-regulation (2006) Curr Opin Immunol, 18, pp. 220-225
• Munn, D.H., Sharma, M.D., Hou, D., Baban, B., Lee, J.R., Antonia, S.J., Messina, J.L., Mellor, A.L., Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes (2004) J Clin Invest, 114, pp. 280-290
• Murata, S., Ladle, B.H., Kim, P.S., Lutz, E.R., Wolpoe, M.E., Ivie, S.E., Smith, H.M., Reilly, R.T., OX40 costimulation synergizes with GM-CSF whole-cell vaccination to overcome established CD8+ T cell tolerance to an endogenous tumor antigen (2006) J Immunol, 176, pp. 974-983
• Nagata, S., Apoptosis by death factor (1997) Cell, 88, pp. 355-365
• Nakano, Y., Kuroda, E., Kito, T., Yokota, A., Yamashita, U., Induction of macrophagic prostaglandin E2 synthesis by glioma cells (2006) J Neurosurg, 104, pp. 574-582
• Nakashima, M., Sonoda, K., Watanabe, T., Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1 (1999) Nat Med, 5, pp. 938-942
• Nefedova, Y., Huang, M., Kusmartsev, S., Bhattacharya, R., Cheng, P., Salup, R., Jove, R., Gabrilovich, D., Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer (2004) J Immunol, 172, pp. 464-474
• North, R.J., Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells (1982) J Exp Med, 155, pp. 1063-1074
• Novellino, L., Castelli, C., Parmiani, G., A listing of human tumor antigens recognized by T cells: March 2004 update (2005) Cancer Immunol Immunother, 54, pp. 187-207
• Onizuka, S., Tawara, I., Shimizu, J., Sakaguchi, S., Fujita, T., Nakayama, E., Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody (1999) Cancer Res, 59, pp. 3128-3133
• Ozaki, Y., Edelstein, M.P., Duch, D.S., Induction of indoleamine 2,3-dioxygenase: A mechanism of the antitumor activity of interferon gamma (1988) Proc Natl Acad Sci USA, 85, pp. 1242-1246
• Paul, P., Rouas-Freiss, N., Khalil-Daher, I., Moreau, P., Riteau, B., Le Gal, F.A., Avril, M.F., Carosella, E.D., HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance (1998) Proc Natl Acad Sci USA, 95, pp. 4510-4515
• Peguet-Navarro, J., Sportouch, M., Popa, I., Berthier, O., Schmitt, D., Portoukalian, J., Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis (2003) J Immunol, 170, pp. 3488-3494
• Phan, G.Q., Yang, J.C., Sherry, R.M., Hwu, P., Topalian, S.L., Schwartzentruber, D.J., Restifo, N.P., Rosenberg, S.A., Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma (2003) Proc Natl Acad Sci USA, 100, pp. 8372-8377
• Poon, R.T., Fan, S.T., Wong, J., Clinical implications of circulating angiogenic factors in cancer patients (2001) J Clin Oncol, 19, pp. 1207-1225
• Prehn, R.T., Lappe, M.A., An immunostimulation theory of tumor development (1971) Transplant Rev, 7, pp. 26-54
• Pure, E., Allison, J.P., Schreiber, R.D., Breaking down the barriers to cancer immunotherapy (2005) Nat Immunol, 6, pp. 1207-1210
• Quezada, S.A., Peggs, K.S., Curran, M.A., Allison, J.P., CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells (2006) J Clin Invest, 116, pp. 1935-1945
• Rabinovich, G.A., Baum, L.G., Tinari, N., Paganelli, R., Natoli, C., Liu, F.T., Iacobelli, S., Galectins and their ligands: Amplifiers, silencers or tuners of the inflammatory response? (2002) Trends Immunol, 23, pp. 313-320
• Rabinovich, G.A., Cumashi, A., Bianco, G.A., Ciavardelli, D., Iurisci, I., D'Egidio, M., Piccolo, E., Iacobelli, S., Synthetic lactulose amines: Novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis (2006) Glycobiology, 16, pp. 210-220
• Rabinovich, G.A., Daly, G., Dreja, H., Tailor, H., Riera, C.M., Hirabayashi, J., Chernajovsky, Y., Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis (1999) J Exp Med, 190, pp. 385-398
• Rabinovich, G.A., Gabrilovich, D., Sotomayor, E.M., Immunosuppressive strategies that are mediated by tumor cells (2007) Annu Rev Immunol, 25, pp. 267-296
• Rabinovich, G.A., Rubinstein, N., Matar, P., Rozados, V., Gervasoni, S., Scharovsky, G.O., The antimetastatic effect of a single low dose of cyclophosphamide involves modulation of galectin-1 and Bcl-2 expression (2002) Cancer Immunol Immunother, 50, pp. 597-603
• Reed, J.C., The Survivin saga goes in vivo (2001) J Clin Invest, 108, pp. 965-969
• Rico, M.J., Matar, P., Gervasoni, S.I., Bonfil, R.D., Calcaterra, N., Scharovsky, O.G., The transition to the metastatic phenotype of rat lymphoma cells involves up-regulation of IL-10 receptor expression and IL-10 secretion (2005) Clin Exp Metastasis, 22, pp. 127-135
• Ritter, G., Livingston, P.O., Ganglioside antigens expressed by human cancer cells (1991) Semin Cancer Biol, 2, pp. 401-409
• Rivoltini, L., Carrabba, M., Huber, V., Castelli, C., Novellino, L., Dalerba, P., Mortarini, R., Parmiani, G., Immunity to cancer: Attack and escape in T lymphocyte-tumor cell interaction (2002) Immunol Rev, 188, pp. 97-113
• Rodgers, J.R., Cook, R.G., MHC class Ib molecules bridge innate and acquired immunity (2005) Nat Rev Immunol, 5, pp. 459-471
• Rodriguez, P.C., Ochoa, A.C., T cell dysfunction in cancer: Role of myeloid cells and tumor cells regulating amino acid availability and oxidative stress (2006) Semin Cancer Biol, 16, pp. 66-72
• Rodriguez, T., Mendez, R., Roberts, C.H., Ruiz-Cabello, F., Dodi, I.A., Lopez Nevot, M.A., Paco, L., Garrido, F., High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity (2005) Cancer Immunol Immunother, 54, pp. 141-148
• Romero, J.M., Jimenez, P., Cabrera, T., Cozar, J.M., Pedrinaci, S., Tallada, M., Garrido, F., Ruiz-Cabello, F., Coordinated downregulation of the antigen presentation machinery and HLA class I/beta2-microglobulin complex is responsible for HLA-ABC loss in bladder cancer (2005) Int J Cancer, 113, pp. 605-610
• Roncarolo, M.G., Bacchetta, R., Bordignon, C., Narula, S., Levings, M.K., Type 1 T regulatory cells (2001) Immunol Rev, 182, pp. 68-79
• Rosenberg, S.A., Progress in human tumour immunology and immunotherapy (2001) Nature, 411, pp. 380-384
• Rouas-Freiss, N., Bruel, S., Menier, C., Marcou, C., Moreau, P., Carosella, E.D., Switch of HLA-G alternative splicing in a melanoma cell line causes loss of HLA-G1 expression and sensitivity to NK lysis (2005) Int J Cancer, 117, pp. 114-122
• Rubinstein, N., Alvarez, M., Zwirner, N.W., Toscano, M.A., Ilarregui, J.M., Bravo, A., Mordoh, J., Rabinovich, G.A., Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege (2004) Cancer Cell, 5, pp. 241-251
• Ryan, A.E., Shanahan, F., O'Connell, J., Houston, A.M., Addressing the "fas counterattack" controversy: Blocking fas ligand expression suppresses tumor immune evasion of colon cancer in vivo (2005) Cancer Res, 65, pp. 9817-9823
• Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., Toda, M., Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases (1995) J Immunol, 155, pp. 1151-1164
• Sanchez-Perez, L., Kottke, T., Diaz, R.M., Ahmed, A., Thompson, J., Chong, H., Melcher, A., Vile, R.G., Potent selection of antigen loss variants of B16 melanoma following inflammatory killing of melanocytes in vivo (2005) Cancer Res, 65, pp. 2009-2017
• Scaffidi, C., Kirchhoff, S., Krammer, P.H., Peter, M.E., Apoptosis signaling in lymphocytes (1999) Curr Opin Immunol, 11, pp. 277-285
• Shimizu, J., Yamazaki, S., Sakaguchi, S., Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity (1999) J Immunol, 163, pp. 5211-5218
• Siegel, C.T., Schreiber, K., Meredith, S.C., Beck-Engeser, G.B., Lancki, D.W., Lazarski, C.A., Fu, Y.X., Schreiber, H., Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein (2000) J Exp Med, 191, pp. 1945-1956
• Sorice, M., Parolini, I., Sansolini, T., Garofalo, T., Dolo, V., Sargiacomo, M., Tai, T., Pavan, A., Evidence for the existence of ganglioside-enriched plasma membrane domains in human peripheral lymphocytes (1997) J Lipid Res, 38, pp. 969-980
• Sorme, P., Qian, Y., Nyholm, P.G., Leffler, H., Nilsson, U.J., Low micromolar inhibitors of galectin-3 based on 3′-derivatization of N-acetyllactosamine (2002) Chembiochem, 3, pp. 183-189
• Spiotto, M.T., Rowley, D.A., Schreiber, H., Bystander elimination of antigen loss variants in established tumors (2004) Nat Med, 10, pp. 294-298
• Steinman, R.M., Hawiger, D., Nussenzweig, M.C., Tolerogenic dendritic cells (2003) Annu Rev Immunol, 21, pp. 685-711
• Stillman, B.N., Hsu, D.K., Pang, M., Brewer, C.F., Johnson, P., Liu, F.T., Baum, L.G., Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death (2006) J Immunol, 176, pp. 778-789
• Strater, J., Walczak, H., Hasel, C., Melzner, I., Leithauser, F., Moller, P., CD95 ligand (CD95L) immunohistochemistry: A critical study on 12 antibodies (2001) Cell Death Differ, 8, pp. 273-278
• Sturm, A., Lensch, M., Andre, S., Kaltner, H., Wiedenmann, B., Rosewicz, S., Dignass, A.U., Gabius, H.J., Human galectin-2: Novel inducer of T cell apoptosis with distinct profile of caspase activation (2004) J Immunol, 173, pp. 3825-3837
• Tanaka, M., Suda, T., Takahashi, T., Nagata, S., Expression of the functional soluble form of human fas ligand in activated lymphocytes (1995) Embo J, 14, pp. 1129-1135
• Terabe, M., Matsui, S., Park, J.M., Mamura, M., Noben-Trauth, N., Donaldson, D.D., Chen, W., Berzofsky, J.A., Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: Abrogation prevents tumor recurrence (2003) J Exp Med, 198, pp. 1741-1752
• Thomas, L., On immunosurveillance in human cancer (1982) Yale J Biol Med, 55, pp. 329-333
• Uyttenhove, C., Pilotte, L., Theate, I., Stroobant, V., Colau, D., Parmentier, N., Boon, T., Van Den Eynde, B.J., Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase (2003) Nat Med, 9, pp. 1269-1274
• Uzzo, R.G., Rayman, P., Kolenko, V., Clark, P.E., Cathcart, M.K., Bloom, T., Novick, A.C., Finke, J.H., Renal cell carcinoma-derived gangliosides suppress nuclear factor-kappaB activation in T cells (1999) J Clin Invest, 104, pp. 769-776
• Van Der Leij, J., Van Den Berg, A., Harms, G., Eschbach, H., Vos, H., Zwiers, P., Van Weeghel, R., Visser, L., Strongly enhanced IL-10 production using stable galectin-1 homodimers (2007) Mol Immunol, 44, pp. 506-513
• Van Elsas, A., Hurwitz, A.A., Allison, J.P., Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation (1999) J Exp Med, 190, pp. 355-366
• Wang, T., Niu, G., Kortylewski, M., Burdelya, L., Shain, K., Zhang, S., Bhattacharya, R., Yu, H., Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells (2004) Nat Med, 10, pp. 48-54
• Weller, M., Malipiero, U., Aguzzi, A., Reed, J.C., Fontana, A., Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation (1995) J Clin Invest, 95, pp. 2633-2643
• Whiteside, T.L., Signaling defects in T lymphocytes of patients with malignancy (1999) Cancer Immunol Immunother, 48, pp. 346-352
• Whiteside, T.L., Herberman, R.B., The role of natural killer cells in immune surveillance of cancer (1995) Curr Opin Immunol, 7, pp. 704-710
• Wieckowski, E., Wang, G.Q., Gastman, B.R., Goldstein, L.A., Rabinowich, H., Granzyme B-mediated degradation of T-cell receptor zeta chain (2002) Cancer Res, 62, pp. 4884-4889
• Wischhusen, J., Friese, M.A., Mittelbronn, M., Meyermann, R., Weller, M., HLA-E protects glioma cells from NKG2D-mediated immune responses in vitro: Implications for immune escape in vivo (2005) J Neuropathol Exp Neurol, 64, pp. 523-528
• Yang, R.Y., Hsu, D.K., Liu, F.T., Expression of galectin-3 modulates T-cell growth and apoptosis (1996) Proc Natl Acad Sci USA, 93, pp. 6737-6742
• Zacarias-Fluck, M.F., Rico, M.J., Gervasoni, S.I., Ilarregui, J.M., Toscano, M.A., Rabinovich, G.A., Scharovsky, G.O., Low dose cyclophosphamide modulates galectin-1 expression and function in an experimental rat lymphoma model (2007) Cancer Immunol Immunother, 56, pp. 237-248
• Zha, Y., Blank, C., Gajewski, T.F., Negative regulation of T-cell function by PD-1 (2004) Crit Rev Immunol, 24, pp. 229-237
• Zhang, X., Huang, H., Yuan, J., Sun, D., Hou, W.S., Gordon, J., Xiang, J., CD4-8- dendritic cells prime CD4+ T regulatory 1 cells to suppress antitumor immunity (2005) J Immunol, 175, pp. 2931-2937
• Zou, W., Immunosuppressive networks in the tumour environment and their therapeutic relevance (2005) Nat Rev Cancer, 5, pp. 263-274
• Zou, W., Regulatory T cells, tumour immunity and immunotherapy (2006) Nat Rev Immunol, 6, pp. 295-307

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