Artículo
Capdevila, D.A.; Álvarez-Paggi, D.; Castro, M.A.; Tórtora, V.; Demicheli, V.; Estrín, D.A.; Radi, R.; Murgida, D.H. "Coupling of tyrosine deprotonation and axial ligand exchange in nitrocytochrome c" (2014) Chemical Communications. 50(20):2592-2594
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Abstract:
Here we report a spectroscopic, electrochemical and computational study of cytochrome c showing that nitration of Tyr74 induces Tyr deprotonation, which is coupled to Met/Lys axial ligand exchange, and results in concomitant gain of peroxidatic activity at physiological pH. © The Royal Society of Chemistry 2014.
Registro:
| Documento: | Artículo |
| Título: | Coupling of tyrosine deprotonation and axial ligand exchange in nitrocytochrome c |
| Autor: | Capdevila, D.A.; Álvarez-Paggi, D.; Castro, M.A.; Tórtora, V.; Demicheli, V.; Estrín, D.A.; Radi, R.; Murgida, D.H. |
| Filiación: | Departamento de Química Inorgánica, Analítica y Química Física, INQUIMAE, Universidad de Buenos Aires-CONICET, Argentina Departamento de Bioquímica, Center for Free Radical and Biomedical Research, Universidad de la República, Montevideo, Uruguay |
| Palabras clave: | cytochrome c; ligand; tyrosine; article; computational fluid dynamics; computer model; controlled study; cyclic potentiometry; deprotonation; electrochemistry; electron transport; molecular dynamics; nitration; nuclear magnetic resonance spectroscopy; pH; proton transport; Computer Simulation; Cytochromes c; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Nitrates; Oxidation-Reduction; Protons; Thermodynamics; Tyrosine |
| Año: | 2014 |
| Volumen: | 50 |
| Número: | 20 |
| Página de inicio: | 2592 |
| Página de fin: | 2594 |
| DOI: | http://dx.doi.org/10.1039/c3cc47207h |
| Título revista: | Chemical Communications |
| Título revista abreviado: | Chem. Commun. |
| ISSN: | 13597345 |
| CODEN: | CHCOF |
| CAS: | cytochrome c, 9007-43-6, 9064-84-0; tyrosine, 16870-43-2, 55520-40-6, 60-18-4 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13597345_v50_n20_p2592_Capdevila |
Referencias:
- Radi, R., (2013) Acc. Chem. Res., 46, p. 550
- Souza, J.M., Peluffo, G., Radi, R., (2008) Free Radical Biol. Med., 45, p. 357
- Forman, H.J., Azzi, A., (1997) FASEB J., 11, p. 374
- Alvarez-Paggi, D., Castro, M.A., Tortora, V., Castro, L., Radi, R., Murgida, D.H., (2013) J. Am. Chem. Soc., 135, p. 4389
- Alvarez-Paggi, D., Martin, D.F., Debiase, P.M., Hildebrandt, P., Marti, M.A., Murgida, D.H., (2010) J. Am. Chem. Soc., 132, p. 5769
- Monari, S., Ranieri, A., Bortolotti, C.A., Peressini, S., Tavagnacco, C., Borsari, M., (2011) Electrochim. Acta, 56, p. 6925
- Battistuzzi, G., Borsari, M., Bortolotti, C.A., Di Rocco, G., Ranieri, A., Sola, M., (2007) J. Phys. Chem. B, 111, p. 10281
- Balakrishnan, G., Hu, Y., Oyerinde, O.F., Su, J., Groves, J.T., Spiro, T.G., (2007) J. Am. Chem. Soc., 129, p. 504
- Bradley, J.M., Silkstone, G., Wilson, M.T., Cheesman, M.R., Butt, J.N., (2011) J. Am. Chem. Soc., 133, p. 19676
- Hanske, J., Toffey, J.R., Morenz, A.M., Bonilla, A.J., Schiavoni, K.H., Pletneva, E.V., (2012) Proc. Natl. Acad. Sci. U. S. A., 109, p. 125
- Kagan, V.E., Bayir, H.A., Belikova, N.A., Kapralov, O., Tyurina, Y.Y., Tyurin, V.A., Jiang, J.F., Borisenko, G., (2009) Free Radical Biol. Med., 46, p. 1439
- Ow, Y.L.P., Green, D.R., Hao, Z., Mak, T.W., (2008) Nat. Rev. Mol. Cell Biol., 9, p. 532
- Sinibaldi, F., Howes, B.D., Droghetti, E., Polticelli, F., Piro, M.C., Di Pierro, D., Fiorucci, L., Santucci, R., (2013) Biochemistry, 52, p. 4578
- Wackerbarth, H., Murgida, D.H., Oellerich, S., Dopner, S., Rivas, L., Hildebrandt, P., (2001) J. Mol. Struct., 563, p. 51
- Rosell, S.I., Ferrer, J.C., Mauk, A.G., (1998) J. Am. Chem. Soc., 120, p. 11234
- Souza, J.M., Castro, L., Cassina, A.M., Batthyany, C., Radi, R., (2008) Methods Enzymol., 441, p. 197
- Abriata, L.A., Cassina, A., Tortora, V., Marin, M., Souza, J.M., Castro, L., Vila, A.J., Radi, R., (2009) J. Biol. Chem., 284, p. 17
- Murgida, D.H., Hildebrandt, P., (2004) Acc. Chem. Res., 37, p. 854
- Balakrishnan, G., Hu, Y., Oyerinde, O.F., Su, J., Groves, J.T., Spiro, T.G., (2007) J. Am. Chem. Soc., 129, p. 504
- Dopner, S., Hildebrandt, P., Rosell, F.I., Mauk, A.G., (1998) J. Am. Chem. Soc., 120, p. 11246
- Dopner, S., Hildebrandt, P., Mauk, A.G., Lenk, H., Stempfle, W., (1996) Spectrochim. Acta, Part A, 52, p. 573
- Assfalg, M., Bertini, I., Dolfi, A., Turano, P., Mauk, A.G., Rosell, F.I., Gray, H.B., (2003) J. Am. Chem. Soc., 125, p. 2913
- Bandi, S., Bowler, B.E., (2011) Biochemistry, 50, p. 10027
- Weinkam, P., Zimmermann, J., Sagle, L.B., Matsuda, S., Dawson, P.E., Wolynes, P.G., Romesberg, F.E., (2008) Biochemistry, 47, p. 13470
- Perroud, T.D., Bokoch, M.P., Zare, R.N., (2005) Proc. Natl. Acad. Sci. U. S. A., 102, p. 17570
- Hoang, L., Maity, H., Krishna, M.M.G., Lin, Y., Englander, S.W., (2003) J. Mol. Biol., 331, p. 37
- Santo-Domingo, J., Demaurex, N., (2012) J. Gen. Physiol., 139, p. 415
Citas:
---------- APA ----------
Capdevila, D.A., Álvarez-Paggi, D., Castro, M.A., Tórtora, V., Demicheli, V., Estrín, D.A., Radi, R.,..., Murgida, D.H. (2014) . Coupling of tyrosine deprotonation and axial ligand exchange in nitrocytochrome c. Chemical Communications, 50(20), 2592-2594.http://dx.doi.org/10.1039/c3cc47207h
---------- CHICAGO ----------
Capdevila, D.A., Álvarez-Paggi, D., Castro, M.A., Tórtora, V., Demicheli, V., Estrín, D.A., et al. "Coupling of tyrosine deprotonation and axial ligand exchange in nitrocytochrome c" . Chemical Communications 50, no. 20 (2014) : 2592-2594.http://dx.doi.org/10.1039/c3cc47207h
---------- MLA ----------
Capdevila, D.A., Álvarez-Paggi, D., Castro, M.A., Tórtora, V., Demicheli, V., Estrín, D.A., et al. "Coupling of tyrosine deprotonation and axial ligand exchange in nitrocytochrome c" . Chemical Communications, vol. 50, no. 20, 2014, pp. 2592-2594.http://dx.doi.org/10.1039/c3cc47207h
---------- VANCOUVER ----------
Capdevila, D.A., Álvarez-Paggi, D., Castro, M.A., Tórtora, V., Demicheli, V., Estrín, D.A., et al. Coupling of tyrosine deprotonation and axial ligand exchange in nitrocytochrome c. Chem. Commun. 2014;50(20):2592-2594.http://dx.doi.org/10.1039/c3cc47207h
