Artículo

Laurimäe, T.; Kinkar, L.; Romig, T.; Omer, R.A.; Casulli, A.; Umhang, G.; Gasser, R.B.; Jabbar, A.; Sharbatkhori, M.; Mirhendi, H.; Ponce-Gordo, F.; Lazzarini, L.E.; Soriano, S.V.; Varcasia, A.; Rostami Nejad, M.; Andresiuk, V.; Maravilla, P.; González, L.M. (...) Saarma, U. "The benefits of analysing complete mitochondrial genomes: Deep insights into the phylogeny and population structure of Echinococcus granulosus sensu lato genotypes G6 and G7" (2018) Infection, Genetics and Evolution. 64:85-94
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Abstract:

Cystic echinococcosis (CE) is a zoonotic disease caused by the larval stage of the species complex Echinococcus granulosus sensu lato. Within this complex, genotypes G6 and G7 have been frequently associated with human CE worldwide. Previous studies exploring the genetic variability and phylogeography of genotypes G6 and G7 have been based on relatively short mtDNA sequences, and the resolution of these studies has often been low. Moreover, using short sequences, the distinction between G6 and G7 has in some cases remained challenging. The aim here was to sequence complete mitochondrial genomes (mitogenomes) to obtain deeper insight into the genetic diversity, phylogeny and population structure of genotypes G6 and G7. We sequenced complete mitogenomes of 94 samples collected from 15 different countries worldwide. The results demonstrated that (i) genotypes G6 and G7 can be clearly distinguished when mitogenome sequences are used; (ii) G7 is represented by two major haplogroups, G7a and G7b, the latter being specific to islands of Corsica and Sardinia; (iii) intensive animal trade, but also geographical isolation, have likely had the largest impact on shaping the genetic structure and distribution of genotypes G6 and G7. In addition, we found phylogenetically highly divergent haplotype from Mongolia (Gmon), which had a higher affinity to G6. © 2018 Elsevier B.V.

Registro:

Documento: Artículo
Título:The benefits of analysing complete mitochondrial genomes: Deep insights into the phylogeny and population structure of Echinococcus granulosus sensu lato genotypes G6 and G7
Autor:Laurimäe, T.; Kinkar, L.; Romig, T.; Omer, R.A.; Casulli, A.; Umhang, G.; Gasser, R.B.; Jabbar, A.; Sharbatkhori, M.; Mirhendi, H.; Ponce-Gordo, F.; Lazzarini, L.E.; Soriano, S.V.; Varcasia, A.; Rostami Nejad, M.; Andresiuk, V.; Maravilla, P.; González, L.M.; Dybicz, M.; Gawor, J.; Šarkūnas, M.; Šnábel, V.; Kuzmina, T.; Saarma, U.
Filiación:Department of Zoology, Institute of Ecology and Earth Sciences, University of Tartu, Vanemuise 46, Tartu, 51003, Estonia
Institute of Zoology, Parasitology Unit, University of Hohenheim, Stuttgart, 70599, Germany
National University Research Institute, National University Sudan, Khartoum, Sudan
World Health Organization Collaborating Centre for the Epidemiology, Detection and Control of Cystic and Alveolar Echinococcosis (in humans and animals), Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, 00161, Italy
European Union Reference Laboratory for Parasites (EURLP), Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, 00161, Italy
Anses, Wildlife Surveillance and Eco-epidemiology Unit, National Reference Laboratory for Echinococcus spp., Nancy Laboratory for Rabies and Wildlife, Malzéville, 54220, France
Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia
Laboratory Science Research Center, Golestan University of Medical Sciences, Gorgan, Iran
Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Department of Parasitology, Faculty of Pharmacy, Complutense University, Plaza Ramón y Cajal s/n, Madrid, 28040, Spain
Department of Microbiology and Parasitology, Faculty of Medical Sciences, Comahue National University, 1400, Neuquén, Buenos Aires, 8300, Argentina
Laboratorio di Parassitologia e Malattie Parassitarie, Ospedale Didattico Veterinario Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Via Vienna 2, Sassari, 07100, Italy
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Laboratorio de Zoonosis Parasitarias, FCEyN, UNMdP, Funes 3350, Mar del Plata, Buenos Aires, 7600, Argentina
Hospital General “Dr. Manuel Gea Gonzalez”, Departamento de Ecologia de Agentes PatogenosDF 14080, Mexico
Parasitology Department, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, 28220, Spain
Department of General Biology and Parasitology, Medical University of Warsaw, 5 Chałubińskiego Str., Warsaw, 02-004, Poland
W. Stefański Institute of Parasitology, Polish Academy of Science, Twarda51/55, Warsaw, 00-818, Poland
Department of Veterinary Pathobiology, Veterinary Academy, Lithuanian University of Health Sciences, Tilžes Street 18, Kaunas, 47181, Lithuania
Institute of Parasitology, Slovak Academy of Sciences, Košice, Hlinkova 3, Košice, 040 01, Slovakia
I.I. Schmalhausen Institute of Zoology, National Academy of Sciences of Ukraine, Kyiv, 01030, Ukraine
Palabras clave:Cystic echinococcosis; Genotype G6; Genotype G7; Hydatid disease; Mitochondrial genome; Zoonosis; cyclooxygenase 1; Article; binding affinity; Corsica; Echinococcus granulosus; Echinococcus granulosus sensu lato; gene sequence; gene structure; genetic variability; genetic variation; genotype; geographic mapping; geography; haplotype; human; life cycle; mitochondrial genome; Mongolia; nonhuman; phylogeny; population differentiation; population structure; priority journal; Sardinia; sequence analysis
Año:2018
Volumen:64
Página de inicio:85
Página de fin:94
DOI: http://dx.doi.org/10.1016/j.meegid.2018.06.016
Título revista:Infection, Genetics and Evolution
Título revista abreviado:Infec. Genet. Evol.
ISSN:15671348
CODEN:IGENC
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15671348_v64_n_p85_Laurimae

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Citas:

---------- APA ----------
Laurimäe, T., Kinkar, L., Romig, T., Omer, R.A., Casulli, A., Umhang, G., Gasser, R.B.,..., Saarma, U. (2018) . The benefits of analysing complete mitochondrial genomes: Deep insights into the phylogeny and population structure of Echinococcus granulosus sensu lato genotypes G6 and G7. Infection, Genetics and Evolution, 64, 85-94.
http://dx.doi.org/10.1016/j.meegid.2018.06.016
---------- CHICAGO ----------
Laurimäe, T., Kinkar, L., Romig, T., Omer, R.A., Casulli, A., Umhang, G., et al. "The benefits of analysing complete mitochondrial genomes: Deep insights into the phylogeny and population structure of Echinococcus granulosus sensu lato genotypes G6 and G7" . Infection, Genetics and Evolution 64 (2018) : 85-94.
http://dx.doi.org/10.1016/j.meegid.2018.06.016
---------- MLA ----------
Laurimäe, T., Kinkar, L., Romig, T., Omer, R.A., Casulli, A., Umhang, G., et al. "The benefits of analysing complete mitochondrial genomes: Deep insights into the phylogeny and population structure of Echinococcus granulosus sensu lato genotypes G6 and G7" . Infection, Genetics and Evolution, vol. 64, 2018, pp. 85-94.
http://dx.doi.org/10.1016/j.meegid.2018.06.016
---------- VANCOUVER ----------
Laurimäe, T., Kinkar, L., Romig, T., Omer, R.A., Casulli, A., Umhang, G., et al. The benefits of analysing complete mitochondrial genomes: Deep insights into the phylogeny and population structure of Echinococcus granulosus sensu lato genotypes G6 and G7. Infec. Genet. Evol. 2018;64:85-94.
http://dx.doi.org/10.1016/j.meegid.2018.06.016