Artículo

Pacin, A.M.; Ciancio Bovier, E.V.; Motta, E.; Resnik, S.L.; Villa, D.; Olsen, M. "Survey of argentinean human plasma for ochratoxin a" (2008) Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment. 25(5):635-641
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Abstract:

The presence of ochratoxin A (OTA) in human blood has been reported for many countries, especially in Europe. However, so far no report exists concerning such a presence in Argentina. The aim of this study was to assess OTA concentration in human plasma in two different areas of Buenos Aires province. OTA was determined by high-performance liquid chromatography (HPLC) in 199 plasma samples from blood donors in Mar del Plata and 236 from General Rodríguez. Solid-phase extraction with Bakerbond® C-18 cartridge and a final purification with Ochraprep® immunoaffinity columns was employed. The limit of quantification of ochratoxin A was 0.019ngml−1 and the confirmation of OTA was by formation of ochratoxin A methyl ester. The results showed that 63.8% of human plasma samples from Mar del Plata and 62.3% from General Rodríguez were positive for OTA, with Winsorized means of 0.15 and 0.43ngml−1, respectively. It is important to continue the research to detect the foods responsible of the presence of OTA in plasma. © 2008 Taylor & Francis Group, LLC.

Registro:

Documento: Artículo
Título:Survey of argentinean human plasma for ochratoxin a
Autor:Pacin, A.M.; Ciancio Bovier, E.V.; Motta, E.; Resnik, S.L.; Villa, D.; Olsen, M.
Filiación:Fundación de Investigaciones Científicas Teresa Benedicta de la Cruz, Centro de Investigación en Micotoxinas, Universidad Nacional de Luján, M. Dorronzoro 141, B6700FTA Luján, Buenos Aires, Argentina
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires (CIC), Argentina
Universidad Nacional de Mar del Plata, Buenos Aires, Argentina
Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina
Dirección Sistemas, Universidad Nacional de Luján, Buenos Aires, Argentina
National Food Administration, Microbiology Division, Uppsala, Sweden
Palabras clave:Exposure; Human plasma; Mycotoxin; Ochratoxin; ochratoxin; ester derivative; ochratoxin; adult; antibody affinity; Argentina; article; blood donor; blood sampling; controlled study; female; food contamination; health survey; high performance liquid chromatography; human; male; priority journal; solid phase extraction; South and Central America; blood analysis; immunoaffinity chromatography; major clinical study; Adult; Agriculture; Argentina; Chromatography, Liquid; Female; Food Contamination; Humans; Male; Ochratoxins; Statistics as Topic
Año:2008
Volumen:25
Número:5
Página de inicio:635
Página de fin:641
DOI: http://dx.doi.org/10.1080/02652030701613709
Título revista:Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment
Título revista abreviado:Food Addit. Contam. Part A Chem. Anal. Control Exposure Risk Assess.
ISSN:19440049
CAS:ochratoxin, 303-47-9, 37203-43-3; Ochratoxins; ochratoxin A, 303-47-9
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19440049_v25_n5_p635_Pacin

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Citas:

---------- APA ----------
Pacin, A.M., Ciancio Bovier, E.V., Motta, E., Resnik, S.L., Villa, D. & Olsen, M. (2008) . Survey of argentinean human plasma for ochratoxin a. Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 25(5), 635-641.
http://dx.doi.org/10.1080/02652030701613709
---------- CHICAGO ----------
Pacin, A.M., Ciancio Bovier, E.V., Motta, E., Resnik, S.L., Villa, D., Olsen, M. "Survey of argentinean human plasma for ochratoxin a" . Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 25, no. 5 (2008) : 635-641.
http://dx.doi.org/10.1080/02652030701613709
---------- MLA ----------
Pacin, A.M., Ciancio Bovier, E.V., Motta, E., Resnik, S.L., Villa, D., Olsen, M. "Survey of argentinean human plasma for ochratoxin a" . Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, vol. 25, no. 5, 2008, pp. 635-641.
http://dx.doi.org/10.1080/02652030701613709
---------- VANCOUVER ----------
Pacin, A.M., Ciancio Bovier, E.V., Motta, E., Resnik, S.L., Villa, D., Olsen, M. Survey of argentinean human plasma for ochratoxin a. Food Addit. Contam. Part A Chem. Anal. Control Exposure Risk Assess. 2008;25(5):635-641.
http://dx.doi.org/10.1080/02652030701613709