The analysis of cardiac damage biomarkers is crucial in the diagnosis and prognosis of acute myocardial infarction. The present work proposes a dynamical model for the analysis of the release in the blood of cardiac troponin T (cTnT). The model, tested against patients data, proves to be an effective tool to extrapolate information of interest to the clinician, like peaks and peak-times of the release curve. Furthermore, the model has been proven efficient to quantitatively differentiate patients with effective and non-effective thrombolysis response, which is a key information to guide revascularization.
A model of cardiac troponin T release in patient with acute myocardial infarction
Procopio A.;MEROLA A;Sabatino J.;Indolfi C.;De Rosa S;Cosentino C
2017-01-01
Abstract
The analysis of cardiac damage biomarkers is crucial in the diagnosis and prognosis of acute myocardial infarction. The present work proposes a dynamical model for the analysis of the release in the blood of cardiac troponin T (cTnT). The model, tested against patients data, proves to be an effective tool to extrapolate information of interest to the clinician, like peaks and peak-times of the release curve. Furthermore, the model has been proven efficient to quantitatively differentiate patients with effective and non-effective thrombolysis response, which is a key information to guide revascularization.File in questo prodotto:
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