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Study to define and verify the personal oral hygiene requirements for extended manned space flight: Oral physiology and microbiology in Skylab manned space missionsMethods for metabolic fingerprinting of pathogenic oral bacteria were developed and the effects of Skylab missions on salivary electrolyte levels were studied. High resolution gas liquid chromatographic (GLC) and pyrolysis-GLC procedures were used to obtain metabolic profiles of closely related bacteria associated with dental caries and periodontal disease. It was found that the GLC procedures provide a practical and reproducible means of obtaining metabolic markers for identifying closely related strains of these organisms. Fractions of stimulated whole saliva samples from the prime and back-up crews of the three Skylab missions were used to measure salivary electrolyte concentrations. All the electrolytes previously reported as having increased in urine and feces during the missions were assessed. Sodium, potassium, calcium, magnesium, phosphorous and chloride were studied. A decrease in sodium and an increase in magnesium were observed, but the mineral imbalances attributable to the mission-related increases in urinary electrolytes were not detected.
Document ID
19750021667
Acquisition Source
Legacy CDMS
Document Type
Contractor Report (CR)
Authors
Brown, L. R. (Texas Univ. Houston, TX, United States)
Date Acquired
September 3, 2013
Publication Date
June 30, 1975
Subject Category
Aerospace Medicine
Report/Patent Number
NASA-CR-144361
Accession Number
75N29740
Funding Number(s)
CONTRACT_GRANT: NAS9-11118
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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