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Studies Relative to the Radiosensitivity of Man: Based on Retrospective Evaluations of Therapeutic and Accidental Total-Body IrradiationThe radiobiologic studies carried out with joint (AEC) ERDA and NASA support during the years 1964 to 1974 at the Medical Division of Oak Ridge Associated Universities are presented. The physiologic data generated were similar in many ways to those previously observed in other medical radiobiologic experiences. They differed, however, in the methods of data acquisition and analysis. Instead of more conventional analytical methods, pulmonary impedance was recorded and quantitated as a measure of radiation-induced gastrointestinal distress and fatiguability. While refinements in dose response related to gastrointestinal distress were accomplished, it was also found that through the use of Fourier analysis of pulmonary impedance waveform GI distress could easily be recognized and quantified even when the initial stages of nausea were below the subjects subjective level of recognition. The results demonstrate that change in pulmonary impedance waveform closely parallel well-defined stages of GI distress, i.e., initial nausea, a progressive increase in nausea, and finally vomiting episodes.
Document ID
19750024660
Acquisition Source
Legacy CDMS
Document Type
Contractor Report (CR)
Authors
Ricks, R. C.
(Oak Ridge Associated Universities Inc., TN, United States)
Lushbaugh, C. C.
(Oak Ridge Associated Universities Inc., TN, United States)
Date Acquired
September 3, 2013
Publication Date
September 1, 1975
Subject Category
Aerospace Medicine
Report/Patent Number
NASA-CR-144439
Accession Number
75N32733
Funding Number(s)
CONTRACT_GRANT: NASA ORDER T-88566
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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