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Applications of luminescent systems to infectious disease methodologyThe characterization of a clinical sample by a simple, fast, accurate, automatable analytical measurement is important in the management of infectious disease. Luminescence assays offer methods rich with options for these measurements. The instrumentation is common to each assay, and the investment is reasonable. Three general procedures were developed to varying degrees of completeness which measure bacterial levels by measuring their ATP, FMN and iron porphyrins. Bacteriuria detection and antibiograms can be determined within half a day. The characterization of the sample for its soluble ATP, FMN or prophyrins was also performed.
Document ID
19760024808
Acquisition Source
Legacy CDMS
Document Type
Preprint (Draft being sent to journal)
Authors
Picciolo, G. L. (NASA Goddard Space Flight Center Greenbelt, MD, United States)
Chappelle, E. W. (NASA Goddard Space Flight Center Greenbelt, MD, United States)
Deming, J. W. (NASA Goddard Space Flight Center Greenbelt, MD, United States)
Mcgarry, M. A. (NASA Goddard Space Flight Center Greenbelt, MD, United States)
Nibley, D. A. (NASA Goddard Space Flight Center Greenbelt, MD, United States)
Okrend, H. (NASA Goddard Space Flight Center Greenbelt, MD, United States)
Thomas, R. R. (NASA Goddard Space Flight Center Greenbelt, MD, United States)
Date Acquired
September 3, 2013
Publication Date
September 1, 1976
Subject Category
Aerospace Medicine
Report/Patent Number
X-726-76-212
NASA-TM-X-71190
Accession Number
76N31896
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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