NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Collections About News Help Login
Back to Results
Oligonucleotides as probes for studying polymerization reactions in dilute aqueous solution. 2: PolycondensationsWe have prepared a (P-32)-labeled oligonucleotide probe carrying a ureido (-NH-CO-NH2) function at its 3'-terminus. This labeled oligomer was used to study polycondensations of urea and formaldehyde and of various phenols and formaldehyde in aqueous solution. The formation of formaldehyde copolymers attached to the amido-function of the probe was monitored by gel electrophoresis. Our results are generally in agreement with those obtained using conventional techniques. Our method is suitable for monitoring potentially prebiotic polycondensation reactions involving formaldehyde.
Document ID
19960016593
Acquisition Source
Headquarters
Document Type
Reprint (Version printed in journal)
Authors
Kolb, Vera (Salk Inst. for Biological Studies San Diego, CA United States)
Orgel, Leslie E. (Salk Inst. for Biological Studies San Diego, CA United States)
Date Acquired
September 6, 2013
Publication Date
January 1, 1995
Subject Category
Inorganic And Physical Chemistry
Report/Patent Number
NAS 1.26:200315
NASA-CR-200315
Accession Number
96N22237
Funding Number(s)
CONTRACT_GRANT: NAGw-1600
CONTRACT_GRANT: NAGw-2881
Distribution Limits
Public
Copyright
Public Use Permitted.

Related Records

There are no records associated with this record.
No Preview Available