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An Inherited Efficiencies Model of Non-Genomic EvolutionA model for the evolution of biological systems in the absence of a nucleic acid-like genome is proposed and applied to model the earliest living organisms -- protocells composed of membrane encapsulated peptides. Assuming that the peptides can make and break bonds between amino acids, and bonds in non-functional peptides are more likely to be destroyed than in functional peptides, it is demonstrated that the catalytic capabilities of the system as a whole can increase. This increase is defined to be non-genomic evolution. The relationship between the proposed mechanism for evolution and recent experiments on self-replicating peptides is discussed.
Document ID
20000081724
Acquisition Source
Ames Research Center
Document Type
Preprint (Draft being sent to journal)
Authors
New, Michael H.
(NASA Ames Research Center Moffett Field, CA United States)
Pohorille, Andrew
(NASA Ames Research Center Moffett Field, CA United States)
Date Acquired
September 7, 2013
Publication Date
March 11, 1999
Subject Category
Life Sciences (General)
Meeting Information
Meeting: BioMedSim ''99 Conference
Location: Noisy-le-Grand,
Country: France
Start Date: April 20, 1999
End Date: April 22, 1999
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
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