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Benchtop Antigen Detection Technique using Nanofiltration and Fluorescent DyesThe designed benchtop technique is primed to detect bacteria and viruses from antigenic surface marker proteins in solutions, initially water. This inclusive bio-immunoassay uniquely combines nanofiltration and near infrared (NIR) dyes conjugated to antibodies to isolate and distinguish microbial antigens, using laser excitation and spectrometric analysis. The project goals include detecting microorganisms aboard the International Space Station, space shuttle, Crew Exploration Vehicle (CEV), and human habitats on future Moon and Mars missions, ensuring astronaut safety. The technique is intended to improve and advance water contamination testing both commercially and environmentally as well. Lastly, this streamlined technique poses to greatly simplify and expedite testing of pathogens in complex matrices, such as blood, in hospital and laboratory clinics.
Document ID
20090020557
Acquisition Source
Glenn Research Center
Document Type
Other - NASA Tech Brief
External Source(s)
http://www.techbriefs.com/component/content/article/5232
Authors
Scardelletti, Maximilian C. (NASA Glenn Research Center Cleveland, OH, United States)
Varaljay, Vanessa (NASA Glenn Research Center Cleveland, OH, United States)
Date Acquired
August 24, 2013
Publication Date
May 1, 2009
Publication Information
Publication: NASA Tech Briefs, May 2009
Subject Category
Life Sciences (General)
Report/Patent Number
LEW-18387-1
Distribution Limits
Public
Copyright
Public Use Permitted.

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IDRelationTitle20090020533Collected WorksNASA Tech Briefs, May 2009
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