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Risk of Therapeutic Failure due to Ineffectiveness of MedicationGiven that terrestrial medical practices must be used as the basis for drug choice and use on missions, there is a possibility that medications used will be ineffective or inappropriate for the actual circumstances encountered on missions. Because the human body undergoes a variety of physiological changes during spaceflight, there is a risk that terrestrial medications may not perform as expected when used during spaceflight. Alterations in physiology due to spaceflight could result in unexpected drug action on the body (pharmacodynamics) or in unusual drug absorption, distribution, metabolism or excretion (pharmacokinetics). The spaceflight environment may also have direct effects on stored drugs themselves, leading to premature inactivation or degradation of stored drugs.
Document ID
20110015816
Acquisition Source
Johnson Space Center
Document Type
Presentation
Authors
Woring, Virginia E. (Universities Space Research Association Houston, TX, United States)
Date Acquired
August 25, 2013
Publication Date
October 10, 2011
Subject Category
Aerospace Medicine
Report/Patent Number
JSC-CN-24713
Meeting Information
Meeting: 2011 Annual Geological Society of America
Location: Nassau Bay, TX
Country: United States
Start Date: October 9, 2011
End Date: October 11, 2011
Distribution Limits
Public
Copyright
Public Use Permitted.

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