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Rift Valley Fever Risk Map Model and Seroprevalence in Selected Wild Ungulates and Camels from KenyaSince the first isolation of Rift Valley fever virus (RVFV) in the 1930s, there have been multiple epizootics and epidemics in animals and humans in sub-Saharan Africa. Prospective climate-based models have recently been developed that flag areas at risk of RVFV transmission in endemic regions based on key environmental indicators that precede Rift Valley fever (RVF) epizootics and epidemics. Although the timing and locations of human case data from the 2006-2007 RVF outbreak in Kenya have been compared to risk zones flagged by the model, seroprevalence of RVF antibodies in wildlife has not yet been analyzed in light of temporal and spatial predictions of RVF activity. Primarily wild ungulate serum samples from periods before, during, and after the 2006-2007 RVF epizootic were analyzed for the presence of RVFV IgM and/or IgG antibody. Results show an increase in RVF seropositivity from samples collected in 2007 (31.8%), compared to antibody prevalence observed from 2000-2006 (3.3%). After the epizootic, average RVF seropositivity diminished to 5% in samples collected from 2008-2009. Overlaying maps of modeled RVF risk assessments with sampling locations indicated positive RVF serology in several species of wild ungulate in or near areas flagged as being at risk for RVF. Our results establish the need to continue and expand sero-surveillance of wildlife species Kenya and elsewhere in the Horn of Africa to further calibrate and improve the RVF risk model, and better understand the dynamics of RVFV transmission.
Document ID
20140017192
Acquisition Source
Goddard Space Flight Center
Document Type
Reprint (Version printed in journal)
Authors
Britch, Seth C.
(Department of Agriculture Gainesville, FL, United States)
Binepal, Yatinder S.
(Kenya National Agricultural Labs. Nairobi, Kenya)
Ruder, Mark G.
(Agricultural Research Service Manhattan, KS, United States)
Kariithi, Henry M.
(Kenya National Agricultural Labs. Nairobi, Kenya)
Linthicum, Kenneth J.
(Department of Agriculture Gainesville, FL, United States)
Anyamba, Assaf
(Universities Space Research Association Greenbelt, MD, United States)
Small, Jennifer L.
(Science Systems and Applications, Inc. Greenbelt, MD, United States)
Tucker, Compton J.
(NASA Goddard Space Flight Center Greenbelt, MD, United States)
Ateya, Leonard O.
(Kenya National Agricultural Labs. Nairobi, Kenya)
Oriko, Abuu A.
(Kenya National Agricultural Labs. Nairobi, Kenya)
Gacheru, Stephen
Wilson, William C.
(Agricultural Research Service Manhattan, KS, United States)
Date Acquired
December 9, 2014
Publication Date
June 28, 2013
Publication Information
Publication: PLOS ONE
Publisher: PLOS One open Access
Volume: 8
Issue: 6
Subject Category
Life Sciences (General)
Report/Patent Number
GSFC-E-DAA-TN14751
Funding Number(s)
CONTRACT_GRANT: NNG11HP16A
PROJECT: USDA #58-5430-005-00D
CONTRACT_GRANT: NNG12HP08C
Distribution Limits
Public
Copyright
Public Use Permitted.
Keywords
Seroprevalence
Camels
Valley
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