NASA GeneLab Concept of OperationsNASA's GeneLab aims to greatly increase the number of scientists that are using data from space biology investigations on board ISS, emphasizing a systems biology approach to the science. When completed, GeneLab will provide the integrated software and hardware infrastructure, analytical tools and reference datasets for an assortment of model organisms. GeneLab will also provide an environment for scientists to collaborate thereby increasing the possibility for data to be reused for future experimentation. To maximize the value of data from life science experiments performed in space and to make the most advantageous use of the remaining ISS research window, GeneLab will apply an open access approach to conducting spaceflight experiments by generating, and sharing the datasets derived from these biological studies in space.Onboard the ISS, a wide variety of model organisms will be studied and returned to Earth for analysis. Laboratories on the ground will analyze these samples and provide genomic, transcriptomic, metabolomic and proteomic data. Upon receipt, NASA will conduct data quality control tasks and format raw data returned from the omics centers into standardized, annotated information sets that can be readily searched and linked to spaceflight metadata. Once prepared, the biological datasets, as well as any analysis completed, will be made public through the GeneLab Space Bioinformatics System webb as edportal. These efforts will support a collaborative research environment for spaceflight studies that will closely resemble environments created by the Department of Energy (DOE), National Center for Biotechnology Information (NCBI), and other institutions in additional areas of study, such as cancer and environmental biology. The results will allow for comparative analyses that will help scientists around the world take a major leap forward in understanding the effect of microgravity, radiation, and other aspects of the space environment on model organisms. These efforts will speed the process of scientific sharing, iteration, and discovery.
Document ID
20150000827
Acquisition Source
Ames Research Center
Document Type
Presentation
Authors
Thompson, Terri (Wyle Labs., Inc. Moffett Field, CA, United States)
Gibbs, Kristina (Wyle Labs., Inc. Moffett Field, CA, United States)
Rask, Jon (Search for Extraterrestrial Intelligence Inst. Moffett Field, CA, United States)
Coughlan, Joseph (NASA Ames Research Center Moffett Field, CA, United States)
Smith, Jeffrey (NASA Ames Research Center Moffett Field, CA, United States)
Date Acquired
January 29, 2015
Publication Date
October 22, 2014
Subject Category
Space Sciences (General)
Report/Patent Number
ARC-E-DAA-TN18494
Meeting Information
Meeting: American Society for Gravitational and Space Research