NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Collections About News Help Login
Back to Results
Mitigating HZE Radiation-Induced Deficits in Marrow-Derived Mesenchymal Progenitor Cells and Skeletal StructureFuture long-duration space exploration beyond the earths magnetosphere will increase human exposure to space radiation and associated risks to skeletal health. We hypothesize that oxidative stress resulting from radiation exposure causes progressive bone loss and dysfunction in associated tissue. In animal studies, increased free radical formation is associated with pathological changes in bone structure, enhanced bone resorption, reduced bone formation and decreased bone mineral density, which can lead to skeletal fragility.
Document ID
20160014637
Acquisition Source
Ames Research Center
Document Type
Presentation
Authors
Globus, Ruth K. (NASA Ames Research Center Moffett Field, CA, United States)
Schreurs, Ann-Sofie (Universities Space Research Association Moffett Field, CA, United States)
Shirazi-Fard, Yasaman (Universities Space Research Association Moffett Field, CA, United States)
Terada, Masahiro (Universities Space Research Association Moffett Field, CA, United States)
Alwood, Joshua (NASA Ames Research Center Moffett Field, CA, United States)
Halloran, Bernard (California Univ. San Francisco, CA, United States)
Tahimic, Candice (Wyle Labs., Inc. Moffett Field, CA, United States)
Date Acquired
December 16, 2016
Publication Date
October 16, 2016
Subject Category
Life Sciences (General)
Report/Patent Number
ARC-E-DAA-TN36340
Meeting Information
Meeting: Radiation Research Conference
Location: Big Island, HI
Country: United States
Start Date: October 16, 2016
End Date: October 19, 2016
Sponsors: Department of Energy, National Space Biomedical Research Inst. (NSBRI), Radiation Research Society, RRS
Funding Number(s)
CONTRACT_GRANT: NCC 9-58
CONTRACT_GRANT: NNA14AB82C
CONTRACT_GRANT: NNH15CO48B
CONTRACT_GRANT: DE-SC0001507
CONTRACT_GRANT: MA02501
Distribution Limits
Public
Copyright
Public Use Permitted.
Keywords
cells
progenitor
mesenchymal

Related Records

There are no records associated with this record.
No Preview Available