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Functionalized Orthoesters as Powerful Building Blocks for the Efficient Preparation of Heteroaromatic Bicycles

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Bastug, Gulluzar [UCL] Eviolitte, Christophe [UCL] Marko, Istvan [UCL]

By combining substituted anilines with functionalized orthoesters, an efficient and connective methodology for the preparation of benzoxazole, benzothiazole, and benzimidazole derivatives has been established. The versatility of this approach enables the development of new libraries of heterocycles containing multifunctional sites.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2012
Language Anglais
Journal information "Organic Letters" - Vol. 14, no.13, p. 3502-3505 (26 juin 2012)
Peer reviewed yes
Publisher American Chemical Society ((United States) [S.l.])
issn 1523-7060
e-issn 1523-7052
Publication status Publié
Affiliation UCL - SST/IMCN/MOST - Molecules, Solids and Reactivity
Keywords heterocycles ; orthoesters ; benzimidazole ; benzoxazole ; benzothiazole
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Bibliographic reference Bastug, Gulluzar ; Eviolitte, Christophe ; Marko, Istvan. Functionalized Orthoesters as Powerful Building Blocks for the Efficient Preparation of Heteroaromatic Bicycles. In: Organic Letters, Vol. 14, no.13, p. 3502-3505 (26 juin 2012)
Permanent URL http://hdl.handle.net/2078.1/128818