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Treated plasma cell lesions of bone with MRI signs of response to treatment: unexpected pathological findings.

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Lecouvet, Frédéric [UCL] De Nayer, Pierre-Pascal [UCL] Garbar, C. Noël, Henri [UCL] Malghem, Jacques [UCL] Maldague, Baudouin [UCL] Vande Berg, Bruno [UCL]

Two cases of treated plasma cell lesions of bone are reported for which contrast-enhanced MRI had suggested necrosis, based on lack of enhancement after gadolinium injection, and in which pathologic examinations revealed the presence of extensive viable neoplastic tissue. These cases highlight the need for cautious interpretation of contrast-enhanced MRI signs of response to treatment and inactivity of lesions in the setting of plasma cell neoplasms.

Document type Article de périodique (Journal article) – Case Reports, Journal Article
Access type Accès restreint
Publication date 1998
Journal information "Skeletal radiology" - Vol. 27, no. 12, p. 692-5 (1998)
Peer reviewed yes
issn 0364-2348
Publication status Publié
Affiliation UCL - MD/RAIM - Département de radiologie et d'imagerie médicale
MESH Subject Adult ; Bone Neoplasms - drug therapy - pathology - radiotherapy ; Bone and Bones - pathology ; Cell Survival ; Contrast Media ; Female ; Gadolinium - diagnostic use ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Multiple Myeloma - drug therapy - pathology ; Necrosis ; Plasma Cells - pathology ; Plasmacytoma - pathology - radiotherapy
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Bibliographic reference Lecouvet, Frédéric ; De Nayer, Pierre-Pascal ; Garbar, C. ; Noël, Henri ; Malghem, Jacques ; et. al. Treated plasma cell lesions of bone with MRI signs of response to treatment: unexpected pathological findings.. In: Skeletal radiology, Vol. 27, no. 12, p. 692-5 (1998)
Permanent URL http://hdl.handle.net/2078.1/27566