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Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators

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Heuser, S Barrett, DG Berg, M. Bonnier, B Kahl, A Weichert, AG

A synthetic route towards cyclopropylic compounds, which act as glucokinase activators is described herein. The present synthesis gives easy and rapid access to a wide variety of either sulfones or sulfonamides starting from readily available late-stage intermediates. (c) 2006 Elsevier Ltd. All rights reserved.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2006
Language Anglais
Journal information "Tetrahedron Letters" - Vol. 47, no. 16, p. 2675-2678 (2006)
Peer reviewed yes
Publisher Pergamon-elsevier Science Ltd (Oxford)
issn 0040-4039
e-issn 1873-3581
Publication status Publié
Affiliation UCL - Autre
Keywords cyclopropanes ; sulfones ; sulfonamides ; glucokinase activators ; halogen-sulfur exchange
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Bibliographic reference Heuser, S ; Barrett, DG ; Berg, M. ; Bonnier, B ; Kahl, A ; et. al. Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators. In: Tetrahedron Letters, Vol. 47, no. 16, p. 2675-2678 (2006)
Permanent URL http://hdl.handle.net/2078.1/38561