Devillers, Ingrid
[UCL]
Declercq, Jean-Paul
[UCL]
De Wergifosse, Bertrand
[UCL]
Bruneau, Marie-Pierre
Tinant, Bernard
[UCL]
Touillaux, Roland
[UCL]
Rees, Jean-François
[UCL]
Marchand-Brynaert, Jacqueline
[UCL]
The reaction of 2-aminopyrazine 1 with the glyoxal derivatives 2a-c gave the bicyclic imidazolopyrazinones 3a,b and the monocyclic N-substituted aminopyrazines 4b and 5c. Compounds 3 feature unique crystallographic characteristics. Their reactivity towards superoxide anion is about five times the reactivity of Trolox(R), while the monocyclic pyrazines are inactive.
Bibliographic reference |
Devillers, Ingrid ; Declercq, Jean-Paul ; De Wergifosse, Bertrand ; Bruneau, Marie-Pierre ; Tinant, Bernard ; et. al. Synthesis, structural characterization and antioxidative properties of aminopyrazine and imidazolopyrazine derivatives. In: Royal Society of Chemistry. Journal: Perkin Transactions 2, , no. 7, p. 1481-1487 (1999) |
Permanent URL |
http://hdl.handle.net/2078.1/44275 |