Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
Zur Ablage hinzufügen
  Lokale TagsFreigabegeschichteDetailsÜbersicht

Freigegeben
Zeitschriftenartikel

Compartmentalizing the embryo: lipids and septate junction mediated barrier function

MPG-Autoren
/persons/resource/persons275762

Ile,  KE
Research Group Extracellular Lipid Signaling in Drosophila Development, Max Planck Institute for Developmental Biology, Max Planck Society;

/persons/resource/persons275483

Renault,  AD
Research Group Extracellular Lipid Signaling in Drosophila Development, Max Planck Institute for Developmental Biology, Max Planck Society;

Externe Ressourcen
Es sind keine externen Ressourcen hinterlegt
Volltexte (beschränkter Zugriff)
Für Ihren IP-Bereich sind aktuell keine Volltexte freigegeben.
Volltexte (frei zugänglich)
Es sind keine frei zugänglichen Volltexte in PuRe verfügbar
Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Ile, K., & Renault, A. (2013). Compartmentalizing the embryo: lipids and septate junction mediated barrier function. Fly, 7(1), 18-22. doi:10.4161/fly.22938.


Zitierlink: https://hdl.handle.net/21.11116/0000-000A-AEAA-3
Zusammenfassung
Lipid phosphate phosphatases (LPPs) are a class of enzymes that can dephosphorylate a number of lysophopholipids in vitro. Analysis of knockouts of LPP family members has demonstrated striking but diverse developmental roles for these enzymes. LPP3 is required for mouse vascular development while the Drosophila LPPs Wunen (Wun) and Wunen2 (Wun2) are required during embryogenesis for germ cell migration and survival. In a recent publication we examined if these fly LPPs have further developmental roles and found that Wun is required for proper tracheal formation. In particular we highlight a role for Wun in septate junction mediated barrier function in the tracheal system. In this paper we discuss further the possible mechanisms by which LPPs may influence barrier activity.