| Title: | A multicenter, prospective, randomized study of selective bile duct cannulation performed by multiple endoscopists: the BIDMEN study |
| Authors: | Kawakami, Hiroshi Browse this author →KAKEN DB |
| Maguchi, Hiroyuki Browse this author |
| Mukai, Tsuyoshi Browse this author |
| Hayashi, Tsuyoshi Browse this author |
| Sasaki, Tamito Browse this author |
| Isayama, Hiroyuki Browse this author |
| Nakai, Yousuke Browse this author |
| Yasuda, Ichiro Browse this author |
| Irisawa, Atsushi Browse this author |
| Niido, Teitetsu Browse this author |
| Okabe, Yoshinobu Browse this author |
| Ryozawa, Shomei Browse this author |
| Itoi, Takao Browse this author |
| Hanada, Keiji Browse this author |
| Kikuyama, Masataka Browse this author |
| Arisaka, Yoshifumi Browse this author |
| Kikuchi, Shogo Browse this author |
| Issue Date: | Feb-2012 |
| Publisher: | Mosby |
| Journal Title: | Gastrointestinal Endoscopy |
| Volume: | 75 |
| Issue: | 2 |
| Start Page: | 362 |
| End Page: | 372 |
| Publisher DOI: | 10.1016/j.gie.2011.10.012 |
| PMID: | 22248605 |
| Abstract: | Background: Wire-guided cannulation (WGC) with a sphincterotome for selective bile duct cannulation (SBDC) has been reported to have a higher success rate and lower incidence of post-ERCP pancreatitis (PEP) than conventional methods in some randomized controlled trials (RCTs) that were both single-center and limited to only a few endoscopists. Objective: To estimate the difference in SBDC according to the method and catheter used in a multicenter and multi-endoscopist study. Design: A prospective multicenter RCT with a 2-by-2 factorial design. Setting: Fifteen referral endoscopy units. Patients: In total, 400 consecutive patients with naïve papilla who were candidates for ERCP were enrolled and randomized. Interventions: Patients were assigned to 4 groups according to combined catheter (sphincterotome (S) or catheter (C)) and method (with/without guidewire (GW)). Main Outcome Measurements: Success rate of SBDC in 10 min, time for SBDC, fluoroscopic time and incidence of complications. Results: There was no significant difference in SBDC success rate between with- and without-GW, between C and S, or between the 4 groups (C+GW, C, S+GW, S). WGC had a tendency to significantly shorten cannulation and fluoroscopy times only in approximately 70% of patients in this study in whom SBDC was achieved in 10 min or less (P = 0.036 and 0.00004, respectively). All 4 groups resulted in similar outcomes in PEP (4%, 5.9%, 2%, and 2.1%, respectively). Limitations: Non double-blind study. Conclusions: WGC appears to significantly shorten cannulation and fluoroscopic times. However, neither the method nor type of catheter used resulted in significant differences in either SBDC success rate or incidence of PEP in this RCT. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/48387 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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