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Highly Enantio- and Diastereoselective Construction of 1,2-Disubstituted Cyclopentane Compounds by Dirhodium(II) Tetrakis[N-phthaloyl-(S)-tert-leucinate]-Catalyzed C–H Insertion Reactions of α-Diazo Esters
Title: | Highly Enantio- and Diastereoselective Construction of 1,2-Disubstituted Cyclopentane Compounds by Dirhodium(II) Tetrakis[N-phthaloyl-(S)-tert-leucinate]-Catalyzed C–H Insertion Reactions of α-Diazo Esters |
Authors: | Minami, Kazushi Browse this author | Tsutsui, Hideyuki Browse this author | Saito, Hiroaki Browse this author | Nambu, Hisanori Browse this author →KAKEN DB | Anada, Masahiro Browse this author →KAKEN DB | Hashimoto, Shunichi6 Browse this author →KAKEN DB |
Authors(alt): | 穴田, 仁洋6 |
Keywords: | asymmetric catalysis | C–C bond formation | C–H insertion | chiral dirhodium(II) carboxylates | cyclization | α-diazo esters |
Issue Date: | 19-Oct-2005 |
Publisher: | Wiley-VCH |
Journal Title: | Advanced Synthesis & Catalysis |
Volume: | 347 |
Issue: | 11-13 |
Start Page: | 1483 |
End Page: | 1487 |
Publisher DOI: | 10.1002/adsc.200505201 |
Abstract: | A highly enantio- and diastereoselective intramolecular C–H insertion reaction of α-diazo esters has been achieved with the use of dirhodium(II) tetrakis[N-phthaloyl-(S)-tert-leucinate] as a catalyst, providing exclusively cis-2-arylcyclopentane-1-carboxylates in up to 95% ee with no evidence of alkene formation. |
Relation: | http://www.interscience.wiley.com/ |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/732 |
Appears in Collections: | 薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 穴田 仁洋
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