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Peri-operative management of multiple tooth extractions in a patient with congenital hypofibrinogenemia receiving anticoagulant therapy
| Title: | Peri-operative management of multiple tooth extractions in a patient with congenital hypofibrinogenemia receiving anticoagulant therapy |
| Authors: | Kakuguchi, Wataru Browse this author →KAKEN DB | | Nakamichi, Yoshiyuki Browse this author | | Kasahara, Kazue Browse this author →KAKEN DB | | Horikawa, Masaaki Browse this author | | Ohiro, Yoichi Browse this author →KAKEN DB |
| Keywords: | fibrinogen | | fibrinogenemia | | hemorrhage | | tooth extraction |
| Issue Date: | 15-Sep-2021 |
| Publisher: | John Wiley & Sons |
| Journal Title: | Oral science international |
| Volume: | 19 |
| Issue: | 22 |
| Start Page: | 106 |
| End Page: | 110 |
| Publisher DOI: | 10.1002/osi2.1120 |
| Abstract: | Congenital fibrinogen disorder is rare and is responsible for the difficulty in achieving hemostasis following surgery. A 75-year-old man was referred to our hospital for the management of gingival hemorrhage. He had a medical history of congenital hypofibrinogenemia, right internal carotid stenosis, hypertension, brain infarction, and Alzheimer's disease. A diagnosis of gingival hemorrhage due to periodontitis of the maxillary left second molar and severe periodontitis necessitating extraction in the maxillary second molars bilaterally, mandibular left second molar, and mandibular right first and third molars was made. A pre-operative hematological examination revealed a fibrinogen level of 53.7 mg/dl. Fibrinogen (3 g) was administered and reached a concentration of 92.8 mg/dl before the surgery. Several episodes of post-operative hemorrhages in the sockets were managed with local hemostatic treatment and splint adjustment. Fibrinogen levels were maintained at 72.5-92.8 mg/dl, until hemostasis was achieved. This case report illustrates the appropriate management of patients with congenital hypofibrinogenemia requiring extraction of multiple teeth. |
| Rights: | This is the peer reviewed version of the following article: Kakuguchi, Wataru, et al. "Peri‐operative management of multiple tooth extractions in a patient with congenital hypofibrinogenemia receiving anticoagulant therapy." Oral Science International., which has been published in final form at https://doi.org/10.1002/osi2.1120. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/86768 |
| Appears in Collections: | 歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 格口 渉
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